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Carravilla, Pablo ; Cruz Rodríguez, Antonio ; Martín-Ugarte, Itziar ; Oar-Arteta, Itziar R. ; Torralba, Johanna ; Apellaniz, Beatriz ; Pérez Gil, Jesús ; Requejo Isidro, José ; Huarte, Nerea ; Nieva, José L. | BIOPHYSICAL SOCIETY | 2017-09-19Membrane fusion induced by the envelope glycoprotein enables the intracellular replication of HIV-1; hence, this process constitutes a major target for antiretroviral compounds. It has been proposed that peptides having propensity to interact wi[...]texto impreso
Huarte, Nerea ; Carravilla, Pablo ; Cruz Rodríguez, Antonio ; Lorizate, Maier ; Nieto-Garay, Jon A. ; Kräusslich, Hans-Georg ; Pérez Gil, Jesús ; Requejo Isidro, José ; Nieva, José L. | Nature Publishing Group | 2016The chemical composition of the human immunodeficiency virus type 1 (HIV-1) membrane is critical for fusion and entry into target cells, suggesting that preservation of a functional lipid bilayer organization may be required for efficient infect[...]texto impreso
Hidalgo Román, Alberto ; García-Mouton, Cristina ; Autilio, Chiara ; Carravilla, Pablo ; Orellana Moraleda, Guillermo ; Islam, Mohammad N. ; Bhattacharya, Jahar ; Bhattacharya, Sunita ; Cruz Rodríguez, Antonio ; Pérez Gil, Jesús | Elsevier | 2020-11-24This work explores the potential for strategizing pulmonary surfactant (PS) for drug delivery over the respiratory air-liquid interface: the interfacial delivery. The efficacy of PS- and interface-assisted drug vehiculization was determined both[...]
