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Tift, M.S. ; Alves de Souza, R.W. ; Weber, J. ; Heinrich, E.C. ; Villafuerte, F.C. ; Malhotra, A. ; Otterbein, L.E. ; Simonson, T.S. | Frontiers Media S.A. | 2020-12-14T16:10:18ZHeme oxygenase (HO) enzymes catalyze heme into biliverdin, releasing carbon monoxide (CO) and iron into circulation. These byproducts of heme degradation can have potent cytoprotective effects in the face of stressors such as hypoxia and ischemi[...]texto impreso
Alva-Diaz, C. ; Alarcon-Ruiz, C.A. ; Pacheco-Barrios, K. ; Mori, N. ; Pacheco-Mendoza, J. ; Traynor, B.J. ; Rivera-Valdivia, A. ; Lertwilaiwittaya, P. ; Bird, T.D. ; Cornejo-Olivas, M. | Frontiers Media S.A. | 2020-12-14T16:06:00ZIntroduction: Patients with Huntington-Like disorders (HLD) comprise a variety of allelic disorders sharing a Huntington phenotype. The hexanucleotide repeat expansion of the C9orf72 gene could explain part of the HLD etiology. We aimed to condu[...]texto impreso
Requena, D. ; Médico, A. ; Chacón, R.D. ; Ramírez, M. ; Marín-Sánchez, O. | Frontiers Media S.A. | 2020-12-14T16:10:06ZCoronavirus disease (COVID-19), caused by the virus SARS-CoV-2, is already responsible for more than 4.3 million confirmed cases and 295,000 deaths worldwide as of May 15, 2020. Ongoing efforts to control the pandemic include the development of [...]texto impreso
Ruetten, M. ; Steinmetz, H.W. ; Thiersch, M. ; Kik, M. ; Vaughan, L. ; Altamura, S. ; Muckenthaler, M.U. ; Gassmann, M. | Frontiers Media S.A. | 2020-12-14T16:10:08ZRestriction of nutrients to pathogens (nutritional immunity) is a critical innate immune response mechanism that operates when pathogens such as Mycobacterium tuberculosis have the potential to evade humoral immunity. Tuberculosis is of growing [...]texto impreso
Carrasco-Escobar, G. ; Fornace, K. ; Wong, D. ; Padilla-Huamantinco, P.G. ; Saldaña-Lopez, J.A. ; Castillo-Meza, O.E. ; Caballero-Andrade, A.E. ; Manrique, E. ; Ruiz-Cabrejos, J. ; Barboza, J.L. ; Rodriguez, H. ; Henostroza, G. ; Gamboa, D. ; Castro, M.C. ; Vinetz, J.M. ; Llanos-Cuentas, A. | Frontiers Media S.A. | 2020-12-14T16:06:13ZHuman movement affects malaria epidemiology at multiple geographical levels; however, few studies measure the role of human movement in the Amazon Region due to the challenging conditions and cost of movement tracking technologies. We developed [...]texto impreso
Fletcher, I.K. ; Stewart-Ibarra, A.M. ; Sippy, R. ; Carrasco-Escobar, G. ; Silva, M. ; Beltran-Ayala, E. ; Ordoñez, T. ; Adrian, J. ; Sáenz, F.E. ; Drakeley, C. ; Jones, K.E. ; Lowe, R. | Frontiers Media S.A. | 2020-12-14T16:06:23ZMalaria is a vector-borne disease of significant public health concern. Despite widespread success of many elimination initiatives, elimination efforts in some regions of the world have stalled. Barriers to malaria elimination include climate an[...]texto impreso
Carrasco-Escobar, G. ; Manrique, E. ; Tello-Lizarraga, K. ; Miranda, J.J. | Frontiers Media S.A. | 2020-12-14T16:06:13ZTo better estimate the travel time to the most proximate health care facility (HCF) and determine differences across heterogeneous land coverage types, this study explored the use of a novel cloud-based geospatial modeling approach. Geospatial d[...]
