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Título:
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Immunologic responses to the major allergen of Olea Europaea in local and systemic allergic rhinitis subjects
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Autores:
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Campo, Paloma ;
Villalba Díaz, Mayte ;
Barrionuevo, Esther ;
Rondón, Carmen ;
Galindo, Luisa ;
Rodríguez, María José ;
López Rodríguez, Juan Carlos ;
Torres, María José ;
Blanca, Miguel ;
Mayorga, Cristobalina
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Tipo de documento:
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texto impreso
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Editorial:
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BioMed Central, 2015
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Dimensiones:
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application/pdf
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Nota general:
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info:eu-repo/semantics/openAccess
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Idiomas:
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Palabras clave:
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Estado = Publicado
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Materia = Ciencias Biomédicas: Medicina: Alergología
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Materia = Ciencias Biomédicas: Biología: Bioquímica
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Tipo = Artículo
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Resumen:
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Evaluate: the in vivo and in vitro responses to nOle e 1 in allergic rhinitis (AR) and local allergic rhinitis (LAR) patients sensitized to olive tree pollen (OL) confirmed by nasal allergen provocation test (NAPT).
Methods: Twelve subjects with AR, 12 with LAR, and 12 subjects as control group (CG) were selected. Skin testing and NAPT with nOle e 1 were performed. ECP and tryptase were measured in nasal lavages before and after NAPT. Serum IgE to OL allergens were measured by ELISA. Basophil activation tests (BAT) with OL and nOle e 1 and dendritic cell maturation/proliferation studies were carried out. Results: All AR (12/12) and 10/12 (83%) of LAR had a +NAPT to nOle e 1. ECP levels in nasal lavages were significantly increased after NAPT in both AR and LAR compared with CG at 15 minutes (p
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En línea:
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https://eprints.ucm.es/33117/1/allergy%20ole%20e1postprint.pdf
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