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Villaverde Cantizano, Gonzalo ; Nairi, Valentina ; Baeza, Alejandro ; Vallet Regí, María | Wiley | 2017-03-28The selective transportation of therapeutic agents to tumoral cells is usually achieved by their conjugation with targeting moieties able to recognize these cells. Unfortunately, simple and static targeting systems usually show selectivity lacks[...]texto impreso
Nairi, Valentina ; Medda, Sara ; Piludu, Marco ; Casula, Maria Francesca ; Vallet Regí, María ; Monduzzi, Maura ; Salis, Andrea | Elsevier | 2018-01-03Biomedical application of nanoparticles is largely associated to their fate in biological media which, in turn, is related to their surface properties. Surface functionalization plays a key role in determining biodegradation, cytotoxicity and bi[...]texto impreso
Nairi, Valentina ; Magnolia, Silvia ; Piludu, Marco ; Nieddu, Mariella ; Caria, Cristian Antonio ; Sogos, Valeria ; Vallet Regí, María ; Monduzzi, Maura ; Salis, Andrea | Elsevier | 2018-02-12Mesoporous silica nanoparticles (MSNs) were functionalized with amino groups (MSN-NH2) and then with hyaluronic acid, a biocompatible biopolymer which can be recognized by CD44 receptors in tumor cells, to obtain a targeting drug delivery system[...]
