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Título:
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Epigenetics in the Eye: An Overview of the Most Relevant Ocular Diseases
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Autores:
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Alkozi, Hanan Awad ;
Franco, Rafael ;
Pintor, Jesús
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Tipo de documento:
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texto impreso
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Editorial:
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Frontiers Media, 2017-10-12
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Dimensiones:
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application/pdf
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Nota general:
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cc_by
info:eu-repo/semantics/openAccess
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Idiomas:
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Palabras clave:
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Estado = Publicado
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Materia = Ciencias Biomédicas: Medicina: Oftalmología
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Tipo = Artículo
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Resumen:
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Sight for mammals is one of the most appreciated senses. In humans there are several factors that contribute to the increment in all kind of eye diseases. This mini-review will focus on some diseases whose prevalence is steadily increasing year after year for non-genetic reasons, namely cataracts, dry eye, and glaucoma. Aging, diet, inflammation, drugs, oxidative stress, seasonal and circadian style-of-live changes are impacting on disease prevalence by epigenetics factors, defined as stable heritable traits that are not explained by changes in DNA sequence. The mini-review will concisely show the data showing epigenetics marks in these diseases and on how knowledge on the epigenetic alterations may guide therapeutic approaches to have a healthy eye.
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En línea:
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https://eprints.ucm.es/45565/1/Pintor_Epigenetics-FrontiersGenetics-2017.pdf
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