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Martín, Humberto ; Shales, Michael ; Fernández-Piñar, Pablo ; Wei, Ping ; Molina, María ; Fiedler, Dorothea ; Shokat, Kevan M. ; Beltrao, Pedro ; Lim, Wendell ; Krogan, Nevan J. | EMBO Press | 2015-04-17Genetic interaction screens have been applied with great success in several organisms to study gene function and the genetic architecture of the cell. However, most studies have been performed under optimal growth conditions even though many fun[...]texto impreso
Fernández-Piñar, Pablo ; Alemán, Ainel ; Sondek, John ; Dohlman, Henrik G. ; Molina, María ; Martín, Humberto | 2012-09-26Intracellular survival of Salmonella relies on the activity of proteins translocated into the host cell by type III secretion systems (T3SS). The protein kinase activity of the T3SS effector SteC is required for F-actin remodeling in host cells,[...]
