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The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae.

Fernández-Piñar, Pablo ; Alemán, Ainel ; Sondek, John ; Dohlman, Henrik G. ; Molina, María ; Martín, Humberto | 2012-09-26

Intracellular survival of Salmonella relies on the activity of proteins translocated into the host cell by type III secretion systems (T3SS). The protein kinase activity of the T3SS effector SteC is required for F-actin remodeling in host cells,[...]

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