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García-Segura, Luis Miguel ; Veiga, Sergio ; Sierra, Amanda ; Melcangi, Roberto C. ; Azcoitia Elías, Iñigo | Elsevier | 2003-09Estradiol, in addition to its participation in neuroendocrine regulation and sexual behavior, has neuroprotective properties. Different types of brain injury induce the expression of the enzyme aromatase in reactive astroglia. This enzyme cataly[...]texto impreso
Mitro, Nico ; Cermenati, Gaia ; Brioschi, Elizabetta ; Abbiati, Federico ; Audano, Matteo ; Giatti, Silvia ; Crestani, Maurizio ; De Fabiani, Emma ; Azcoitia Elías, Iñigo ; García-Segura, Luis Miguel ; Caruso, Donatella ; Melcangi, Roberto C. | Elsevier | 2014-09Diabetic peripheral neuropathy causes a decrease in the levels of dihydroprogesterone and 5- androstane-3,17-diol (3-diol) in the peripheral nerves. These two neuroactive steroids exert protective effects, by mechanisms that still remain elusive[...]texto impreso
Acaz Fonseca, Estefanía ; Ortiz Rodriguez, Ana ; Azcoitia Elías, Iñigo ; García-Segura, Luis Miguel ; Arévalo, María Ángeles | Springer | 2019-04-03In the nervous system, Notch pathway has a prominent role in the control of neuronal morphology and in the determination of the astrocyte fate. However, the role of Notch in morphological astrocyte plasticity is unknown. Here, we have explored t[...]
