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Resumen:
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Dry eye disease (DED) is a multifactorial disease of the ocular surface considered one of the most frequently encountered ocular conditions seen by eye care practitioners. Nowadays, DED is estimated to affect between 5 ? 50% of the worldwide population. Furthermore, the prevalence of DED increases linearly with age which makes DED a growing public health concern as the global population of older people is expected to be more than double its current amount by 2050. According to DED classification, the aqueous deficient dry eye (ADDE) and evaporative dry eye (EDE) are the two major DED types and are considered to exist on a continuum rather than as separate entities. Despite this, according to the current DED understanding, an evaporative component is more common than an ADDE component. Currently, the Meibomian gland dysfunction (MGD) is considered the leading cause of EDE. This condition may result in alteration of the tear film, symptoms of eye irritation, clinically apparent inflammation and ocular surface disease. Therefore, any change that occurs in the morphology of the MG or in its secretion has an important clinical impact...
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