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Backer, Lynn de ; Cerrada, Alejandro ; Pérez Gil, Jesús ; Smedt, Stefaan C. de ; Raemdonck, Koen | Elsevier | 2015Many pathologies of the respiratory tract are inadequately treated with existing small molecule-based therapies. The emergence of RNA interference (RNAi) enables the post-transcriptional silencing of key molecular disease factors that cannot rea[...]texto impreso
Cerrada, Alejandro ; Haller, Thomas ; Cruz Rodríguez, Antonio ; Pérez Gil, Jesús | Cross Mark | 2015-12Pulmonary surfactant (PS) is an essential complex of lipids and specific proteins synthesized in alveolar type II pneumocytes, where it is assembled and stored intracellularly as multilayered organelles known as lamellar bodies (LBs). Once secre[...]
