| Título: | Effect of nutritional supplement based on melatonin on the intraocular pressure in normotensive subjects |
| Autores: | Carracedo Rodríguez, Juan Gonzalo ; Martínez Águila, Alejandro ; Rodríguez Pomar, Candela ; Bodas Romero, Julia ; Sánchez Naves, Juan ; Pintor, Jesús |
| Tipo de documento: | texto impreso |
| Editorial: | Springer Verlag, 2019-10-24 |
| Dimensiones: | application/pdf |
| Nota general: |
info:eu-repo/semantics/openAccess info:eu-repo/semantics/restrictedAccess |
| Idiomas: | |
| Palabras clave: | Estado = Publicado , Materia = Ciencias Biomédicas: Medicina: Bioquímica , Materia = Ciencias Biomédicas: Medicina: Oftalmología , Materia = Ciencias Biomédicas: Enfermería , Fisioterapia y Podología: Nutrición , Materia = Ciencias Biomédicas: Óptica y optometría: Anatomía ocular , Tipo = Artículo |
| Resumen: |
Purpose: To evaluate the effect of a new nutritional supplement based on melatonin on the intraocular pressure (IOP) in normotensive subjects. Patients and methods: A short-term prospective study was designed. Sixty-seven normotensive subjects were recruited. Patients were divided into two groups. The daily group (DG) (n?=?18) was instructed to take the supplement between 22:00 and 23:00 (before sleeping) for 3 consecutive days. IOP was measured from 10.00 to 11.00 am the day before treatment and during the 3 days of experiment. The acute group (AG) (n?=?49) was instructed to take the supplement after the second measure (11.00) of the second day. IOP was measured 1 h and just before the intake of the supplement and 1 and 2 h after. All measurements in this group were taken 1 day before without any supplement (control) and the day of experiment. Results: The DG group showed a significant decrease in IOP after supplement intake in all days of experiment, from 14.9?±?3.4 mm Hg to 13.8?±?2.9 mm Hg after 3 days of experiment (p value?0.001). For AG, IOP did not change during the control day; however, a reduction of 1 mm Hg was found 2 and 3 h after supplement intake, from 15.7?±?2.5 mm Hg to 14.7?±?2.5 mm Hg and 15.1?±?2.7 mm Hg, respectively, being statistically significant (p value?0.001). Conclusion: The supplement based on melatonin was able to reduce the IOP in normotensive subjects after 2 h of intake. Moreover, the daily intake showed a reduction in IOP during the 3 days of experiment. |
| En línea: | https://eprints.ucm.es/58571/7/Carracedo_INTE-D-19-00363_R1-ePRINT.pdf |
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