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Neonatal treatment with a pegylated leptin antagonist induces sexually dimorphic effects on neurones and glial cells, and on markers of synaptic plasticity in the developing rat hippocampal formation

López Gallardo, Meritxell ; Antón Fernández, A. ; Llorente, R. ; Mela Rivas, Virginia ; Llorente Berzal, Álvaro ; Prada, C. ; Viveros, María Paz | Wiley | 2015-08

The present study aimed to better understand the role of the neonatal leptin surge, which peaks on postnatal day (PND)9–10, on the development of the hippocampal formation. Accordingly, male and female rats were administered with a pegylated lep[...]

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