Título: | Natural product-related multitarget-directed ligands for the potential treatment of neurodegenerative diseases |
Autores: | Cores Esperón, Ángel |
Tipo de documento: | texto impreso |
Editorial: | Universidad Complutense de Madrid, 2019-11-27 |
Dimensiones: | application/pdf |
Nota general: | info:eu-repo/semantics/openAccess |
Idiomas: | |
Palabras clave: | Estado = No publicado , Materia = Ciencias Biomédicas: Medicina: Farmacología , Materia = Ciencias Biomédicas: Medicina: Neurociencias , Materia = Ciencias Biomédicas: Farmacia: Farmacología , Materia = Ciencias Biomédicas: Farmacia: Farmacopeas , Materia = Ciencias Biomédicas: Farmacia: Química farmaceútica , Materia = Ciencias Biomédicas: Farmacia: Salud Pública , Materia = Ciencias Biomédicas: Farmacia: Tecnología farmaceútica , Tipo = Tesis |
Resumen: | Neurodegenerative diseases are characterized by the loss of neurons in the brain and/or spinal cord and constitute one of the most important health problems worldwide. Although these diseases have different etiologies and clinical manifestations, they share many mechanistic pathways, including: protein misfolding, neuroinflammation, impaired mitochondrial function, increase in oxidative stress, mitochondrial disfunction, alterations in calcium homeostasis, etc... |
En línea: | https://eprints.ucm.es/id/eprint/59744/1/T41882.pdf |
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