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Título:
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EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology
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Autores:
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Reche, Pedro A ;
Zhang, Hong ;
Glutting, John-Paul ;
Reinherz, Ellis L
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Tipo de documento:
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texto impreso
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Editorial:
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Oxford University Press, 2005
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Dimensiones:
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application/pdf
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Nota general:
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info:eu-repo/semantics/openAccess
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Idiomas:
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Palabras clave:
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Estado = Publicado
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Materia = Ciencias Biomédicas: Medicina: Inmunología
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Materia = Ciencias Biomédicas: Biología: Biología molecular
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Materia = Ciencias: Informática: Bioinformática
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Tipo = Artículo
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Resumen:
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EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/
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En línea:
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https://eprints.ucm.es/id/eprint/9332/1/26.Reche_etal_Bioinf_2005.pdf
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