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Título:
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Corneal Segmentation Analysis Increases Glaucoma Diagnostic Ability of Optic Nerve Head Examination, Heidelberg Retina Tomograph's Moorfield's Regression Analysis, and Glaucoma Probability Score
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Autores:
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Sáenz Francés, Federico ;
Jañez Escalada, Luis ;
Berrozpe Villabona, Clara ;
Borrego Sanz, Lara ;
Morales Fernández, Laura ;
Acebal Montero, Alejandra ;
Méndez Hernández, Carmen D. ;
Martínez de la Casa, Jose Maria ;
Santos Bueso, Enrique ;
García Sánchez, Julián ;
García Feijoo, Julián
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Tipo de documento:
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texto impreso
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Editorial:
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Hindawi Publishing Corporation, 2015
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Dimensiones:
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application/pdf
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Nota general:
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cc_by
info:eu-repo/semantics/openAccess
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Idiomas:
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Palabras clave:
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Estado = Publicado
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Materia = Ciencias Biomédicas: Medicina: Oftalmología
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Materia = Ciencias Biomédicas: Óptica y optometría: Técnicas de la imagen
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Tipo = Artículo
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Resumen:
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Purpose. To study whether a corneal thickness segmentation model, consisting in a central circular zone of 1?mm radius centered at the corneal apex (zone I) and five concentric rings of 1?mm width (moving outwards: zones II to VI), could boost the diagnostic accuracy of Heidelberg Retina Tomograph's (HRT's) MRA and GPS. Material and Methods. Cross-sectional study. 121 healthy volunteers and 125 patients with primary open-angle glaucoma. Six binary multivariate logistic regression models were constructed (MOD-A1, MOD-A2, MOD-B1, MOD-B2, MOD-C1, and MOD-C2). The dependent variable was the presence of glaucoma. In MOD-A1, the predictor was the result (presence of glaucoma) of the analysis of the stereophotography of the optic nerve head (ONH). In MOD-B1 and MOD-C1, the predictor was the result of the MRA and GPS, respectively. In MOD-B2 and MOD-C2, the predictors were the same along with corneal variables: central, overall, and zones I to VI thicknesses. This scheme was reproduced for model MOD-A2 (stereophotography along with corneal variables). Models were compared using the area under the receiver operator characteristic curve (AUC). Results. MOD-A1-AUC: 0.771; MOD-A2-AUC: 0.88; MOD-B1-AUC: 0.736; MOD-B2-AUC: 0.845; MOD-C1-AUC: 0.712; MOD-C2-AUC: 0.838. Conclusion. Corneal thickness variables enhance ONH assessment and HRT's MRA and GPS diagnostic capacity.
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En línea:
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https://eprints.ucm.es/id/eprint/41292/1/corneal%20segmentation-Hindawi-2015.pdf
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