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Documentos disponibles de esta editorial (170)
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White, Sara E. ; Harvey, Steven A. ; Meza, Graciela ; Llanos, Alejandro ; Guzman, Mitchel ; Gamboa, Dionicia ; Vinetz, Joseph M. | BMC | 2018-11-30T02:09:28ZBACKGROUND: A transmission-blocking vaccine (TBV) to prevent malaria-infected humans from infecting mosquitoes has been increasingly considered as a tool for malaria control and elimination. This study tested the hypothesis that a malaria TBV wo[...]![]()
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Sempou, Emily ; Biasini, Emiliano ; Pinzon-Olejua, Alejandro ; Harris, David-A. ; Malaga-Trillo, Edward | BMC | 2019-02-06T14:45:59ZBACKGROUND: Prions and amyloid-beta (Abeta) oligomers trigger neurodegeneration by hijacking a poorly understood cellular signal mediated by the prion protein (PrP) at the plasma membrane. In early zebrafish embryos, PrP-1-dependent signals cont[...]![]()
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Accinelli, Roberto A. ; Llanos, Oscar ; Lopez, Lidia M. ; Pino, Maria I. ; Bravo, Yeny A. ; Salinas, Veronica ; Lazo, Maria ; Noda, Julio R. ; Sanchez-Sierra, Marita ; Zarate, Lacey ; da Silva, Joao ; Gianella, Fabiola ; Kheirandish-Gozal, Leila ; Gozal, David | BMC | 2020-06-10T18:11:34ZBACKGROUND: Symptoms of sleep apnea are markedly increased in children exposed to smoke from biomass fuels and are reduced by kitchen stoves that improve indoor biomass pollution. However, the impact of adherence to the use of improved stoves ha[...]![]()
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Abstract
Background
Adolescent pregnancies are a common phenomenon that can have both positive and negative consequences. The rights framework allows us to explore adolescent pregnancies not just as isolated events, but in relat[...]
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Bouton, Tara C. ; Phillips, Patrick P. J. ; Mitnick, Carole D. ; Peloquin, Charles A. ; Eisenach, Kathleen ; Patientia, Ramonde F. ; Lecca, Leonid ; Gotuzzo, Eduardo ; Gandhi, Neel R. ; Butler, Donna ; Diacon, Andreas H. ; Martel, Bruno ; Santillan, Juan ; Hunt, Kathleen Robergeau ; Vargas, Dante ; von Groote-Bidlingmaier, Florian ; Seas, Carlos ; Dianis, Nancy ; Moreno-Martinez, Antonio ; Horsburgh, C. Robert | BMC | 2019-01-25T16:59:36ZBACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the optimal dose of fluoroqu[...]![]()
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Jimenez, Alfons ; Rees-Channer, Roxanne R. ; Perera, Rushini ; Gamboa, Dionicia ; Chiodini, Peter L. ; Gonzalez, Iveth J. ; Mayor, Alfredo ; Ding, Xavier C. | BMC | 2019-01-25T15:02:16ZBACKGROUND: Rapid diagnostic tests (RDTs) are today the most widely used method for malaria diagnosis and are recommended, alongside microscopy, for the confirmation of suspected cases before the administration of anti-malarial treatment. The di[...]![]()
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Manrique, Paulo ; Hoshi, Mari ; Fasabi, Manuel ; Nolasco, Oscar ; Yori, Pablo ; Calderon, Martiza ; Gilman, Robert H. ; Kosek, Margaret N. ; Vinetz, Joseph M. ; Gamboa, Dionicia | BMC | 2019-02-06T14:53:06ZBACKGROUND: Several platforms have been used to generate the primary data for microsatellite analysis of malaria parasite genotypes. Each has relative advantages but share a limitation of being time- and cost-intensive. A commercially available [...]![]()
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Folayan, Morenike Oluwatoyin ; El Tantawi, Maha ; Aly, Nourhan M. ; Al-Batayneh, Ola B. ; Schroth, Robert J. ; Castillo, Jorge L. ; Virtanen, Jorma I. ; Gaffar, Balgis O. ; Amalia, Rosa ; Kemoli, Arthur ; Vulkovic, Ana ; Feldens, Carlos A. ; ECCAG | BMC | 2020-07-14T00:01:11ZBACKGROUND: The aim of this study was to assess the relationship between early childhood caries (ECC) in 3–5-year-old children, seven indicators of poverty and the indicator of monetary poverty in low- and middle-income countries (LICs, MICs). M[...]![]()
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Fung, J. ; Gelaye, B. ; Zhong, Q.Y. ; Rondon, M.B. ; Sánchez, S.E. ; Barrios, Y.V. ; Hevner, K. ; Qiu, C. ; Williams, M.A. | BMC | 2019-04-24T18:23:51ZBackground: Antepartum depression is one of the leading causes of maternal morbidity and mortality in the prenatal period. There is accumulating evidence for the role of brain-derived neurotrophic factor (BDNF) in the pathophysiology of depressi[...]![]()
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Davila Cordova, Jennifer Estefanía ; Tapia Aguirre, Vilma ; Vasquez Apestegui, Vanessa ; Ordoñez Ibarguen, Luis ; Vu, Bryan N. ; Steenland, Kyle ; Gonzales, Gustavo F. | BMC | 2020-07-14T00:01:06ZBACKGROUND: Lima is one of the more polluted cities in Latin America. High levels of PM(2.5) have been shown to increase health center outpatient visits of respiratory diseases. METHODS: Health center outpatient visits for children![]()
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Torres, Katherine ; Bachman, Christine M. ; Delahunt, Charles B. ; Alarcon Baldeon, Jhonatan ; Alava, Freddy ; Gamboa Vilela, Dionicia ; Proux, Stephane ; Mehanian, Courosh ; McGuire, Shawn K. ; Thompson, Clay M. ; Ostbye, Travis ; Hu, Liming ; Jaiswal, Mayoore S. ; Hunt, Victoria M. ; Bell, David | BMC | 2018-11-30T02:09:30ZBACKGROUND: Microscopic examination of Giemsa-stained blood films remains a major form of diagnosis in malaria case management, and is a reference standard for research. However, as with other visualization-based diagnoses, accuracy depends on i[...]![]()
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Scliar, M.O. ; Gouveia, M.H. ; Benazzo, A. ; Ghirotto, S. ; Fagundes, N.J. ; Leal, T.P. ; Magalhães, W.C. ; Pereira, L. ; Rodrigues, M.R. ; Soares-Souza, G.B. ; Cabrera, L. ; Berg, D.E. ; Gilman, R.H. ; Bertorelle, G. ; Tarazona-Santos, E. | BMC | 2020-06-10T18:11:37ZBackground: Archaeology reports millenary cultural contacts between Peruvian Coast-Andes and the Amazon Yunga, a rainforest transitional region between Andes and Lower Amazonia. To clarify the relationships between cultural and biological evolut[...]![]()
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Buttenheim, Alison M. ; Levy, Michael Z. ; Castillo-Neyra, Ricardo ; McGuire, Molly ; Toledo Vizcarra, Amparo M. ; Mollesaca Riveros, Lina M. ; Meza, Julio ; Borrini-Mayori, Katty ; Náquira, César ; Behrman, Jere ; Paz-Soldan, Valerie A. | BMC | 2019-12-06T21:04:43ZBACKGROUND: Individual behavior change is a critical ingredient in efforts to improve global health. Central to the focus on behavior has been a growing understanding of how the human brain makes decisions, from motivations and mindsets to uncon[...]![]()
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Peiris, David ; Thompson, Simon R. ; Beratarrechea, Andrea ; Cardenas, Maria Kathia ; Diez-Canseco, Francisco ; Goudge, Jane ; Gyamfi, Joyce ; Kamano, Jemima Hoine ; Irazola, Vilma ; Johnson, Claire ; Kengne, Andre P. ; Keat, Ng Kien ; Miranda, J. Jaime ; Mohan, Sailesh ; Mukasa, Barbara ; Ng, Eleanor ; Nieuwlaat, Robby ; Ogedegbe, Olugbenga ; Ovbiagele, Bruce ; Plange-Rhule, Jacob ; Praveen, Devarsetty ; Salam, Abdul ; Thorogood, Margaret ; Thrift, Amanda G. ; Vedanthan, Rajesh ; Waddy, Salina P. ; Webster, Jacqui ; Webster, Ruth ; Yeates, Karen ; Yusoff, Khalid | BMC | 2019-02-06T14:52:36ZBACKGROUND: The Global Alliance for Chronic Diseases comprises the majority of the world's public research funding agencies. It is focussed on implementation research to tackle the burden of chronic diseases in low- and middle-income countries a[...]![]()
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Hernández-Vásquez, A. ; Alarcon-Ruiz, C.A. ; Bendezu-Quispe, G. ; Comandé, D. ; Rosselli, D. | BMC | 2018-11-30T23:41:31ZBackground: Biosimilars could be a promising option to help decrease healthcare costs and expand access to treatment. There is no previous evidence of a global bibliometric analysis on biosimilars. Therefore, we aimed to assess the quantity and [...]![]()
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Francis, Elizabeth R. ; Kuo, Chin-Chi ; Bernabé-Ortiz, Antonio ; Nessel, Lisa ; Gilman, Robert H. ; Checkley, William ; Miranda, J. Jaime ; Feldman, Harold I. | BMC | 2019-02-06T14:52:15ZBACKGROUND: The silent progression of chronic kidney diseases (CKD) and its association with other chronic diseases, and high treatment costs make it a great public health concern worldwide. The population burden of CKD in Peru has yet to be fu[...]![]()
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Abstract
Background
Incubators are organizations that support the growth of new and typically technology-based enterprises, by providing business support services that bring together human and financial capital. Although the tra[...]
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Infections with Bartonella bacilliformis result in Carrion's disease in humans. In the first phase of infection, the pathogen causes a hemolytic fever ("Oroya fever") with case-fatality rates as high as ~90% in untreated patients, followed by a [...]![]()
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Garcia-Quintanilla, Meritxell ; Dichter, Alexander A. ; Guerra, Humberto ; Kempf, Volkhard A. J. | BMC | 2019-07-04T16:59:23ZInfections with Bartonella bacilliformis result in Carrion's disease in humans. In the first phase of infection, the pathogen causes a hemolytic fever ("Oroya fever") with case-fatality rates as high as ~90% in untreated patients, followed by a[...]![]()
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Menezes, S.M. ; Decanine, D. ; Brassat, D. ; Khouri, R. ; Schnitman, S.V. ; Kruschewsky, R. ; López, G. ; Álvarez, C. ; Talledo, M. ; Gotuzzo, E. ; Vandamme, A.-M. ; Galvão-Castro, B. ; Liblau, R. ; Weyenbergh, J.V. | BMC | 2020-06-10T18:12:16ZBackground: Human T-cell lymphotropic virus (HTLV-1) is the causative agent of the incapacitating, neuroinflammatory disease HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Currently, there are no disease-modifying therapies[...]![]()
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Zafra-Tanaka, J.H. ; Goicochea-Lugo, S. ; Villarreal-Zegarra, D. ; Taype-Rondan, A. | BMC | 2019-12-06T20:57:46ZBackground: Clinical Practice Guidelines (CPGs) should follow an adequate methodology using an evidence-based approach in order to provide reliable recommendations. However, little is known regarding the quality of CPGs for Depression, which pre[...]![]()
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Zafra-Tanaka, Jessica Hanae ; Goicochea-Lugo, Sergio ; Villarreal-Zegarra, David ; Taype-Rondan, Álvaro | BMC | 2019-07-04T16:59:24ZBACKGROUND: Clinical Practice Guidelines (CPGs) should follow an adequate methodology using an evidence-based approach in order to provide reliable recommendations. However, little is known regarding the quality of CPGs for Depression, which pre[...]![]()
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De Vries, Y.A. ; Al-Hamzawi, A. ; Alonso, J. ; Borges, G. ; Bruffaerts, R. ; Bunting, B. ; Caldas-De-Almeida, J.M. ; Cia, A.H. ; de Girolamo, G. ; Dinolova, R.V. ; Esan, O. ; Florescu, S. ; Gureje, O. ; Haro, J.M. ; Hu, C. ; Karam, E.G. ; Karam, A. ; Kawakami, N. ; Kiejna, A. ; Kovess-Masfety, V. ; Lee, S. ; Mneimneh, Z. ; Navarro-Mateu, F. ; Piazza, M. ; Scott, K. ; ten Have, M. ; Torres, Y. ; Viana, M.C. ; Kessler, R.C. ; de Jonge, P. ; Aguilar-Gaxiola, S. ; Al-Kaisy, M.S. ; Andrade, L.H. ; Benjet, C. ; Bromet, E.J. ; De Almeida, J.M.C. ; Cardoso, G. ; Chatterji, S. ; Degenhardt, L. ; Demyttenaere, K. ; Hinkov, H. ; Hu, C.-Y. ; Karam, A.N. ; Lépine, J.-P. ; Levinson, D. ; McGrath, J. ; Medina-Mora, M.E. ; Moskalewicz, J. ; Pennell, B.-E. ; Posada-Villa, J. ; Scott, K.M. ; Slade, T. ; Stagnaro, J.C. ; Stein, D.J. ; Whiteford, H. ; Williams, D.R. ; Wojtyniak, B. | BMC | 2019-07-04T16:59:24ZBackground: Specific phobia (SP) is a relatively common disorder associated with high levels of psychiatric comorbidity. Because of its early onset, SP may be a useful early marker of internalizing psychopathology, especially if generalized to m[...]![]()
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Reis-Cunha, J.L. ; Rodrigues-Luiz, G.F. ; Valdivia, H.O. ; Baptista, R.P. ; Mendes, T.A.O. ; Loss de Morais, G. ; Guedes, R. ; Macedo, A.M. ; Bern, C. ; Gilman, R.H. ; Talavera Lopez, C. ; Andersson, B. ; Vasconcelos, A.T. ; Bartholomeu, D.C. | BMC | 2019-04-24T18:23:51ZBackground: Trypanosoma cruzi, the etiologic agent of Chagas disease, is currently divided into six discrete typing units (DTUs), named TcI-TcVI. CL Brener, the reference strain of the T. cruzi genome project, is a hybrid with a genome assembled[...]![]()
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Lazo-Porras, Maria ; Ortiz-Soriano, Victor ; Moscoso-Porras, Miguel ; Runzer-Colmenares, Fernando M. ; Malaga, German ; Jaime Miranda, J. | BMC | 2019-01-25T15:02:20ZBACKGROUND: Previous studies have shown that hypertension is a risk factor for cognitive impairment, but whether this association is also present in extremely poor populations in Low Middle Income Countries settings remains to be studied. Unders[...]![]()
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Salmón-Mulanovich, Gabriela ; Powell, Amy-R. ; Hartinger-Pena, Stella-M. ; Schwarz, Lara ; Bausch, Daniel-G. ; Paz-Soldan, Valerie-A. | BMC | 2019-02-06T14:45:58ZBACKGROUND: Madre de Dios is located in the southeastern Amazonian region of Peru. Rodents have been estimated to be the reservoirs for up to 50 % of emerging zoonotic pathogens, including a host of viruses, bacteria, and parasites. As part of a[...]![]()
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Comparative genomic analysis of Leishmania (Viannia) peruviana and Leishmania (Viannia) braziliensis
Valdivia, Hugo O. ; Reis-Cunha, Joao L. ; Rodrigues-Luiz, Gabriela F. ; Baptista, Rodrigo P. ; Baldeviano, G. Christian ; Gerbasi, Robert V. ; Dobson, Deborah E. ; Pratlong, Francine ; Bastien, Patrick ; Lescano, Andres G. ; Beverley, Stephen M. ; Bartholomeu, Daniella C. | BMC | 2019-02-06T14:52:14ZBACKGROUND: The Leishmania (Viannia) braziliensis complex is responsible for most cases of New World tegumentary leishmaniasis. This complex includes two closely related species but with different geographic distribution and disease phenotypes, [...]![]()
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Singh, Neha-S. ; Huicho, Luis ; Afnan-Holmes, Hoviyeh ; John, Theopista ; Moran, Allisyn-C. ; Colbourn, Tim ; Grundy, Chris ; Matthews, Zoe ; Maliqi, Blerta ; Mathai, Matthews ; Daelmans, Bernadette ; Requejo, Jennifer ; Lawn, Joy-E. | BMC | 2019-02-06T14:45:59ZBACKGROUND: Evaluating health systems and policy (HSP) change and implementation is critical in understanding reproductive, maternal, newborn and child health (RMNCH) progress within and across countries. Whilst data for health outcomes, covera[...]![]()
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Mann, Carlyn ; Ng, Courtney ; Akseer, Nadia ; Bhutta, Zulfiqar-A. ; Borghi, Josephine ; Colbourn, Tim ; Hernandez-Pena, Patricia ; Huicho, Luis ; Malik, Muhammad-Ashar ; Martinez-Alvarez, Melisa ; Munthali, Spy ; Salehi, Ahmad-Shah ; Tadesse, Mekonnen ; Yassin, Mohammed ; Berman, Peter | BMC | 2019-02-06T14:45:55ZBACKGROUND: Countdown to 2015 (Countdown) supported countries to produce case studies that examine how and why progress was made toward the Millennium Development Goals (MDGs) 4 and 5. Analysing how health-financing data explains improvements in[...]![]()
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Pollard, S.L. ; Williams, D.L. ; Breysse, P.N. ; Baron, P.A. ; Grajeda, L.M. ; Gilman, R.H. ; Jaime Miranda, J. ; Checkley, W. | BMC | 2020-06-10T18:11:31ZBackground: Burning biomass fuels indoors for cooking is associated with high concentrations of particulate matter (PM) and carbon monoxide (CO). More efficient biomass-burning stoves and chimneys for ventilation have been proposed as solutions [...]![]()
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Caffrey, D. ; Jaime Miranda, J. ; Gilman, R.H. ; Dávila-Roman, V.G. ; Cabrera, L. ; Dowling, R. ; Stewart, T. ; Bernabé-Ortiz, A. ; Wise, R. ; León-Velarde, F. ; Checkley, W. | BMC | 2020-06-10T18:11:38ZBackground: We sought to determine if adult residents living at high altitude have developed sufficient adaptation to a hypoxic environment to match the functional capacity of a similar population at sea level. To test this hypothesis, we compar[...]![]()
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Lee, Sky W. ; Deiss, Robert G. ; Segura, Eddy R. ; Clark, Jesse L. ; Lake, Jordan E. ; Konda, Kelika A. ; Coates, Thomas J. ; Caceres, Carlos F. | BMC | 2019-02-06T14:52:16ZBACKGROUND: Increased HIV testing frequency among high-risk populations such as men who have sex with men (MSM) and male-to-female transgender women (TW) can lead to earlier treatment and potentially reduce HIV transmission. METHODS: We analyzed[...]![]()
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Kojima, N. ; Siebert, J. C. ; Maecker, H. ; Rosenberg-Hasson, Y. ; Leon, S. R. ; Vargas, S. K. ; Konda, K. A. ; Caceres, C. F. ; Klausner, J. D. | BMC | 2019-12-06T20:57:50ZBACKGROUND: Current syphilis tests cannot distinguish between active and past syphilis among patients with serofast rapid plasma reagin (RPR) titers. We investigated whether cytokine profiles might provide insight in the differentiation of activ[...]![]()
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Kojima, N. ; Siebert, J. C. ; Maecker, H. ; Rosenberg-Hasson, Y. ; Leon, S. R. ; Vargas, S. K. ; Konda, K. A. ; Caceres, C. F. ; Klausner, J. D. | BMC | 2019-07-04T16:59:27ZBackground. Current syphilis tests cannot distinguish between active and past syphilis among patients with serofast rapid plasma reagin (RPR) titers. We investigated whether cytokine profiles might provide insight in the differentiation of activ[...]![]()
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Pajuelo, Monica J. ; Anticona Huaynate, Cynthia ; Correa, Malena ; Mayta Malpartida, Holger ; Ramal Asayag, Cesar ; Seminario, Juan R. ; Gilman, Robert H. ; Murphy, Laura ; Oberhelman, Richard A. ; Paz-Soldan, Valerie A. | BMC | 2018-11-30T03:10:43ZBACKGROUND: Delays in receiving adequate care for children suffering from pneumonia can be life threatening and have been described associated with parents' limited education and their difficulties in recognizing the severity of the illness. The[...]![]()
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Wingfield, Tom ; Boccia, Delia ; Tovar, Marco A. ; Huff, Doug ; Montoya, Rosario ; Lewis, James J. ; Gilman, Robert H. ; Evans, Carlton A. | BMC | 2019-02-06T14:52:15ZBackground. Cash transfers are key interventions in the World Health Organisation’s post-2015 global TB policy. However, evidence guiding TB-specific cash transfer implementation is limited. We designed, implemented and refined a novel TB-specif[...]![]()
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Riddell, Michaela A. ; Edwards, Nancy ; Thompson, Simon R. ; Bernabé-Ortiz, Antonio ; Praveen, Devarsetty ; Johnson, Claire ; Kengne, Andre P. ; Liu, Peter ; McCready, Tara ; Ng, Eleanor ; Nieuwlaat, Robby ; Ovbiagele, Bruce ; Owolabi, Mayowa ; Peiris, David ; Thrift, Amanda G. ; Tobe, Sheldon ; Yusoff, Khalid | BMC | 2019-01-25T15:18:33ZBACKGROUND: The imperative to improve global health has prompted transnational research partnerships to investigate common health issues on a larger scale. The Global Alliance for Chronic Diseases (GACD) is an alliance of national research fundi[...]![]()
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Morales Ruiz, Sandra ; Bendezu, Jorge ; Choque Guevara, Ricardo ; Montesinos, Ricardo ; Requena, David ; Choque Moreau, Luz ; Montalvan Avalos, Angela ; Fernandez-Diaz, Manolo | BMC | 2019-03-05T15:23:25ZBackground: Infectious coryza (IC) is an acute respiratory disease of growing chickens and layers caused by Avibacterium paragallinarum. The development of tools that allow rapid pathogen detection is necessary in order to avoid disease dissemin[...]![]()
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Altez-Fernandez, Carlos ; Ortiz, Victor ; Mirzazadeh, Majid ; Zegarra, Luis ; Seas, Carlos ; Ugarte-Gil, Cesar | BMC | 2019-01-25T15:18:33ZBACKGROUND: Genitourinary tuberculosis is the third most common form of extrapulmonary tuberculosis. Diagnosis is difficult because of unspecific clinical manifestations and low accuracy of conventional tests. Unfortunately, the delayed diagnosi[...]![]()
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Anticona Huaynate, Cynthia Fiorella ; Pajuelo Travezaño, Mónica Jehnny ; Correa, Malena ; Mayta Malpartida, Holger ; Oberhelman, Richard ; Murphy, Laura L. ; Paz-Soldan, Valerie A. | BMC | 2019-02-06T14:52:14ZBACKGROUND: Worldwide, rural communities face barriers when accessing health services. In response, numerous initiatives have focused on fostering technological innovations, new management approaches and health policies. Research suggests that t[...]![]()
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McCloskey, Morgan L. ; Tarazona-Meza, Carla E. ; Jones-Smith, Jessica C. ; Miele, Catherine H. ; Gilman, Robert H. ; Bernabé-Ortiz, Antonio ; Miranda, J. Jaime ; Checkley, William | BMC | 2019-01-25T15:18:33ZBACKGROUND: Diet and activity are thought to worsen with urbanization, thereby increasing risk of obesity and chronic diseases. A better understanding of dietary and activity patterns across the urbanization divide may help identify pathways, an[...]![]()
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Nguyen, H. Bryant ; Jaehne, Anja-Kathrin ; Jayaprakash, Namita ; Semler, Matthew-W. ; Hegab, Sara ; Yataco, Angel-Coz ; Tatem, Geneva ; Salem, Dhafer ; Moore, Steven ; Boka, Kamran ; Gill, Jasreen-Kaur ; Gardner-Gray, Jayna ; Pflaum, Jacqueline ; Domecq, Juan-Pablo ; Hurst, Gina ; Belsky, Justin-B. ; Fowkes, Raymond ; Elkin, Ronald-B. ; Simpson, Steven-Q. ; Falk, Jay-L. ; Singer, Daniel-J. ; Rivers, Emanuel-P. | BMC | 2019-02-06T14:51:42ZPrior to 2001 there was no standard for early management of severe sepsis and septic shock in the emergency department. In the presence of standard or usual care, the prevailing mortality was over 40-50 %. In response, a systems-based approach, [...]![]()
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Moreno-Gutierrez, Diamantina ; Rosas-Aguirre, Angel ; Llanos-Cuentas, Alejandro ; Bilcke, Joke ; Barboza, José Luis ; Hayette, Marie-Pierre ; Contreras-Mancilla, Juan ; Aguirre, Kristhian ; Gamboa, Dionicia ; Rodriguez, Hugo ; Speybroeck, Niko ; Beutels, Philippe | BMC | 2020-07-14T00:02:35ZBackground: Case management is one of the principal strategies for malaria control. This study aimed to estimate the economic costs of uncomplicated malaria case management and explore the influence of health-seeking behaviours on those costs. M[...]![]()
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Siddharthan, Trishul ; Pollard, Suzanne L. ; Quaderi, Shumonta A. ; Mirelman, Andrew J. ; Cardenas, Maria Kathia ; Kirenga, Bruce ; Rykiel, Natalie A. ; Miranda, J. Jaime ; Shrestha, Laxman ; Chandyo, Ram K. ; Cattamanchi, Adithya ; Michie, Susan ; Barber, Julie ; Checkley, William ; Hurst, John R. | BMC | 2018-11-30T03:10:45ZBACKGROUND: Chronic obstructive pulmonary disease (COPD) is the end result of a susceptible individual being exposed to sufficiently deleterious environmental stimuli. More than 90% of COPD-related deaths occur in low- and middle-income countrie[...]![]()
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Zafra-Tanaka, Jessica Hanae ; Pacheco-Barrios, Kevin ; Tellez, Walter Andree ; Taype-Rondan, Álvaro | BMC | 2019-07-04T16:59:31ZBACKGROUND: Dog-assisted therapy (DAT) is a non-pharmacological intervention based on the interaction between patients and dogs, which has been proposed to help adults with dementia. However, evidence to support it is lacking. Thus, we aim to ev[...]![]()
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Zafra-Tanaka, J.H. ; Pacheco-Barrios, K. ; Tellez, W.A. ; Taype-Rondan, A. | BMC | 2019-12-06T20:57:50ZBackground: Dog-assisted therapy (DAT) is a non-pharmacological intervention based on the interaction between patients and dogs, which has been proposed to help adults with dementia. However, evidence to support it is lacking. Thus, we aim to ev[...]![]()
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Fandiño-Del-Rio, Magdalena ; Goodman, Dina ; Kephart, Josiah L. ; Miele, Catherine H. ; Williams, Kendra N. ; Moazzami, Mitra ; Fung, Elizabeth C. ; Koehler, Kirsten ; Davila-Roman, Victor G. ; Lee, Kathryn A. ; Nangia, Saachi ; Harvey, Steven A. ; Steenland, Kyle ; Gonzales, Gustavo F. ; Checkley, William ; Cardiopulmonary outcomes and Household Air Pollution | BMC | 2019-01-25T16:59:37ZBACKGROUND: Biomass fuel smoke is a leading risk factor for the burden of disease worldwide. International campaigns are promoting the widespread adoption of liquefied petroleum gas (LPG) in resource-limited settings. However, it is unclear if t[...]![]()
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Moransard, M. ; Bednar, M. ; Frei, K. ; Gassmann, M. ; Ogunshola, O. O. | BMC | 2019-01-25T15:18:34ZBACKGROUND: Treatment with erythropoietin (Epo) in experimental autoimmune encephalomyelitis (EAE), the rodent model of multiple sclerosis (MS), has consistently been shown to ameliorate disease progression and improve overall outcome. The effec[...]![]()
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Pinzón-Olejua, A. ; Welte, C. ; Abdesselem, H. ; Malaga-Trillo, E. ; Stuermer, C.A.O. | BMC | 2020-06-10T18:12:16ZBackground: As a consequence of gene/genome duplication, the RTN4/Nogo gene has two counterparts in zebrafish: rtn4a and rtn4b. The shared presence of four specific amino acid motifs-M1 to M4-in the N-terminal region of mammalian RTN4, and zebra[...]![]()
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Henry Bonnie ; Orrego Elena ; Rojas Alejandro ; Yassi Annalee ; Parra Jorge ; Solis Fernanda ; Beltran Efrain ; Breilh Jaime ; Spiegel Jerry M ; Bowie William R ; Pearce Laurie ; Gaibor Juan ; Velasquez Patricio ; Concepcion Miriam ; Parkes Margot | BMC | 2019-09-23T13:38:57ZAbstract
Background
The
Sustainably Managing Environmental Health Risk in Ecuador project was launched in 2004 as a partnership linking a large Canadian university with leading Cuban and Mexican institutes to strengthen[...]![]()
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Gomez-Puerta, Lucho ; Vargas-Calla, Ana ; Castillo, Yesenia ; Lopez-Urbina, Maria Teresa ; Dorny, Pierre ; Garcia, Hector H. ; Gonzalez, Armando E. ; O'Neal, Seth E. | BMC | 2019-07-04T16:59:33ZBACKGROUND: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using EL[...]![]()
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Gomez-Puerta, L. ; Vargas-Calla, A. ; Castillo, Y. ; Lopez-Urbina, M.T. ; Dorny, P. ; Garcia, H.H. ; Gonzalez, A.E. ; O'Neal, S.E. | BMC | 2019-12-06T21:02:58ZBackground: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using EL[...]![]()
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Lora, Meredith H. ; Reimer-McAtee, Melissa J. ; Gilman, Robert H. ; Lozano, Daniel ; Saravia, Ruth ; Pajuelo, Monica ; Bern, Caryn ; Castro, Rosario ; Espinoza, Magaly ; Vallejo, Maya ; Solano, Marco ; Challapa, Roxana ; Torrico, Faustino | BMC | 2019-02-06T14:52:14ZBackground. Myrciaria dubia is an Amazonian fruit shrub that produces numerous bioactive phytochemicals, but is best known by its high L-ascorbic acid (AsA) content in fruits. Pronounced variation in AsA content has been observed both within and[...]![]()
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Bendezu, Jorge ; Villasis, Elizabeth ; Morales Ruiz, Sandra ; Garro, Katherine ; Infante, Beronica ; Gutierrez-Loli, Renzo ; Rodriguez, Pamela ; Fernandez-Diaz, Manolo ; Gamboa, Dionicia ; Torres, Katherine | BMC | 2019-12-06T21:02:56ZBACKGROUND: Different antigens are needed to characterize Plasmodium falciparum infection in terms of seroreactivity and targets for invasion inhibition, in order to guide and identify the proper use of such proteins as tools for the development[...]![]()
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Lainhart, William ; Bickersmith, Sara A. ; Nadler, Kyle J. ; Moreno, Marta ; Saavedra, Marlon P. ; Chu, Virginia M. ; Ribolla, Paulo E. ; Vinetz, Joseph M. ; Conn, Jan E. | BMC | 2019-02-06T14:53:06ZBACKGROUND: The major Neotropical malaria vector, Anopheles darlingi, was reintroduced into the Iquitos, Loreto, Peru area during the early 1990s, where it displaced other anophelines and caused a major malaria epidemic. Since then, case numbers[...]![]()
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Huicho, Luis ; Huayanay-Espinoza, Carlos-A. ; Herrera-Perez, Eder ; Nino-de-Guzman, Jessica ; Rivera-Ch, Maria ; Restrepo-Mendez, Maria-Clara ; Barros, Aluisio-J. D. | BMC | 2019-02-06T14:45:35ZBACKGROUND: Peru has impressively reduced its neonatal mortality rate (NMR). We aimed, for the period 2000-2013, to: (a) describe national and district NMR variations over time; (b) assess NMR trends by wealth quintile and place of residence; (c[...]![]()
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Emily Evens ; Michele Lanham ; Karin Santi ; Juana Cooke ; Kathleen Ridgeway ; Giuliana Morales ; Caleb Parker ; Claire Brennan ; Marjan de Bruin ; Pavel Chladni Desrosiers ; Xenia Diaz ; Marta Drago ; Roger McLean ; Modesto Mendizabal ; Dirk Davis ; Rebecca B. Hershow ; Robyn Dayton | BMC | 2019-09-25T21:46:24ZAbstract Background Female sex workers, MSM, and transgender women—collectively referred to as key populations (KPs)—are disproportionately affected by gender-based violence (GBV) and HIV, yet little is known about the violence they face, its ge[...]![]()
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Paz-Soldan, Valerie-A. ; Bauer, Karin-M. ; Lenhart, Audrey ; Cordova-Lopez, Jhonny-J. ; Elder, John-P. ; Scott, Thomas-W. ; McCall, Philip-J. ; Kochel, Tadeusz-J. ; Morrison, Amy-C. | BMC | 2019-02-06T14:45:57ZBACKGROUND: Dengue is an arthropod-borne viral disease responsible for approximately 400 million infections annually; the only available method of prevention is vector control. It has been previously demonstrated that insecticide treated curtain[...]![]()
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Abstract Background Thus far, little work in bioethics has specifically focused on global health research priority-setting. Yet features of global health research priority-setting raise ethical considerations and concerns related to health justi[...]![]()
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Hartinger, Stella M. ; Nuño, Nestor ; Hattendorf, Jan ; Verastegui, Hector ; Karlen, Walter ; Ortiz, Mariela ; Mäusezahl, Daniel | BMC | 2020-07-14T00:01:15ZBACKGROUND: Exposure to unhealthy environments and inadequate child stimulation are main risk factors that affect children’s health and wellbeing in low- and middle-income countries. Interventions that simultaneously address several risk factors[...]![]()
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Huicho, Luis ; Molina, Cristina ; Diez-Canseco, Francisco ; Lema, Claudia ; Miranda, J. Jaime ; Huayanay-Espinoza, Carlos A. ; Lescano, Andres G. | BMC | 2019-02-06T14:52:36ZBACKGROUND: Deployment of health workforce in rural areas is critical to reach universal health coverage. Students' perceptions towards practice in rural areas likely influence their later choice of a rural post. We aimed at exploring perceptio[...]![]()
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Huicho, Luis ; Huayanay-Espinoza, Carlos A. ; Herrera-Perez, Eder ; Segura, Eddy R. ; Niño de Guzman, Jessica ; Rivera-Ch, Maria ; Barros, Aluisio J. D. | BMC | 2019-01-25T15:18:35ZBACKGROUND: Stunting prevalence in children less than 5 years has remained stagnated in Peru from 1992 to 2007, with a rapid reduction thereafter. We aimed to assess the role of different predictors on stunting reduction over time and across dep[...]![]()
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Genetic diversity of Nyssorhynchus (Anopheles) darlingi related to biting behavior in western Amazon
Campos, M. ; Alonso, D.P. ; Conn, J.E. ; Vinetz, J.M. ; Emerson, K.J. ; Ribolla, P.E.M. | BMC | 2019-12-06T21:02:58ZBackground: In the Amazon Basin, Nyssorhynchus (Anopheles) darlingi is the most aggressive and effective malaria vector. In endemic areas, behavioral aspects of anopheline vectors such as host preference, biting time and resting location post bl[...]![]()
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Genetic diversity of Nyssorhynchus (Anopheles) darlingi related to biting behavior in western Amazon
Campos, Melina ; Alonso, Diego Peres ; Conn, Jan E. ; Vinetz, Joseph M. ; Emerson, Kevin J. ; Ribolla, Paulo Eduardo Martins | BMC | 2019-07-04T16:59:36ZBACKGROUND: In the Amazon Basin, Nyssorhynchus (Anopheles) darlingi is the most aggressive and effective malaria vector. In endemic areas, behavioral aspects of anopheline vectors such as host preference, biting time and resting location post b[...]![]()
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Gelabert, Pere ; Ferrando-Bernal, Manuel ; Dios, Toni de ; Mattorre, Benedetta ; Campoy, Elena ; Gorostiza, Amaya ; Patin, Etienne ; González Martín, Antonio ; Lalueza-Fox, Carles | BMC | 2019-03-06Background: Bioko is one of the few islands that exist around Africa, the most genetically diverse continent on the planet. The native Bantu-speaking inhabitants of Bioko, the Bubi, are believed to have colonized the island about 2000 years ago.[...]![]()
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Torres-Roman, J. Smith ; Urrunaga-Pastor, Diego ; Avilez, Jose L. ; Helguero-Santin, Luis M. ; Malaga, German | BMC | 2018-11-30T17:17:12ZBACKGROUND: Childhood obesity is emerging as a major public health problem worldwide. To date, most studies of obesity and overweight in Peru are focused on adults, with few of them involving children, a population at a critical stage of develop[...]![]()
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Li, Ling ; Li, Sheyu ; Liu, Jiali ; Deng, Ke ; Busse, Jason-W. ; Vandvik, Per-Olav ; Wong, Evelyn ; Sohani, Zahra-N. ; Bala, Malgorzata-M. ; Rios, Lorena-P. ; Malaga, German ; Ebrahim, Shanil ; Shen, Jiantong ; Zhang, Longhao ; Zhao, Pujing ; Chen, Qunfei ; Wang, Yingqiang ; Guyatt, Gordon-H. ; Sun, Xin | BMC | 2019-02-06T14:45:36ZBACKGROUND: The effect of glucagon-like peptide-1(GLP-1) receptor agonists on heart failure remains uncertain. We therefore conducted a systematic review to assess the possible impact of GLP-1 agonists on heart failure or hospitalization for he[...]![]()
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BACKGROUND: Monitoring graduates' views of their learning experiences is important to ensure programme standards and further improvement. This study evaluated graduates' satisfaction with and attitudes towards a Master programme in Dental Public[...]![]()
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Ortiz Catedral, Luis ; Brunton, Dianne ; Stidworthy, Mark F. ; Elsheikha, Hany M. ; Pennycott, Tom ; Schulze, Christoph ; Braun, Michael ; Wink, Michael ; Gerlach, Helga ; Pendl, Helene ; Gruber, Achim D. ; Ewen, John ; Pérez Tris, Javier ; Valki?nas, Gediminas ; Olias, Philipp | BMC | 2019-01-17Background: Haemoproteus and Plasmodium species are widespread avian blood parasites. Several Plasmodium species are known for their high virulence and have caused significant declines in naïve bird populations. The impact of closely related Hae[...]![]()
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Calderon, Maria ; Alvarado-Villacorta, Rosa ; Barrios, Miguel ; Quiroz-Robladillo, Devy ; Guzman Naupay, Doris Rocio ; Obregon, Ana ; Calderon Chavez, Sthefanny ; Glaser, Lisa ; Carnero, Andres M. ; Cortez-Vergara, Carla ; Iglesias Quilca, David ; Colque Gonzales, Jose ; Moore, David | BMC | 2019-12-06T20:57:40ZBACKGROUND: Health needs and access to health care is a huge challenge in developing countries, especially in some isolated indigenous communities. Amantani is an island located at 3854 m above sea level in Lake Titicaca, Peru. There is no offic[...]![]()
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Calderon, Maria ; Alvarado-Villacorta, Rosa ; Barrios, Miguel ; Quiroz-Robladillo, Devy ; Guzman Naupay, Doris Rocio ; Obregon, Ana ; Calderon Chavez, Sthefanny ; Glaser, Lisa ; Carnero, Andres M. ; Cortez-Vergara, Carla ; Iglesias Quilca, David ; Colque Gonzales, Jose ; Moore, David | BMC | 2019-07-04T17:00:15ZBACKGROUND: Health needs and access to health care is a huge challenge in developing countries, especially in some isolated indigenous communities. Amantani is an island located at 3854m above sea level in Lake Titicaca, Peru. There is no offici[...]![]()
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Annika Laukamp ; Luise Prüfer-Krämer ; Florian Fischer ; Alexander Krämer | BMC | 2019-09-23T13:39:07ZAbstract Background The war in Syria has led to the biggest refugee crisis of our time. Unaccompanied asylum seeking adolescents (UASA) are a particularly vulnerable subgroup of refugees. This study aims to describe the weight status, health beh[...]![]()
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Beran, David ; Miranda, J. Jaime ; Cardenas, Maria Kathia ; Bigdeli, Maryam | BMC | 2019-02-06T14:52:35ZBACKGROUND: As many challenges exist for access to diabetes care in developing countries, the International Insulin Foundation developed a Rapid Assessment tool and implemented this approach to identify barriers to care and propose concrete reco[...]![]()
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Carrasco-Escobar, Gabriel ; Miranda-Alban, Julio ; Fernandez-Minope, Carlos ; Brouwer, Kimberly C. ; Torres, Katherine ; Calderón, Maritza ; Gamboa, Dionicia ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. | BMC | 2019-01-25T15:18:36ZBACKGROUND: The incidence of malaria due both to Plasmodium falciparum and Plasmodium vivax in the Peruvian Amazon has risen in the past 5 years. This study tested the hypothesis that the maintenance and emergence of malaria in hypoendemic regio[...]![]()
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Saavedra, Marlon P. ; Conn, Jan E. ; Alava, Freddy ; Carrasco-Escobar, Gabriel ; Prussing, Catharine ; Bickersmith, Sara A. ; Sangama, Jorge L. ; Fernandez-Minope, Carlos ; Guzman, Mitchel ; Tong, Carlos ; Valderrama, Carlos ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Moreno, Marta | BMC | 2019-12-06T20:57:48ZBACKGROUND: Malaria remains an important public health problem in Peru where incidence has been increasing since 2011. Of over 55,000 cases reported in 2017, Plasmodium vivax was the predominant species (76%), with P. falciparum responsible for[...]![]()
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Saavedra, Marlon P. ; Conn, Jan E. ; Alava, Freddy ; Carrasco-Escobar, Gabriel ; Prussing, Catharine ; Bickersmith, Sara A. ; Sangama, Jorge L. ; Fernandez-Minope, Carlos ; Guzman, Mitchel ; Tong, Carlos ; Valderrama, Carlos ; Vinetz, Joseph M. ; Gamboa, Dionicia ; Moreno, Marta | BMC | 2019-08-08T15:23:47ZBACKGROUND: Malaria remains an important public health problem in Peru where incidence has been increasing since 2011. Of over 55,000 cases reported in 2017, Plasmodium vivax was the predominant species (76%), with P. falciparum responsible for[...]![]()
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Seyoum, Dinberu ; Yewhalaw, Delenasaw ; Duchateau, Luc ; Brandt, Patrick ; Rosas-Aguirre, Angel ; Speybroeck, Niko | BMC | 2019-01-25T15:18:36ZBACKGROUND: The global decline of malaria burden and goals for elimination has led to an increased interest in the fine-scale epidemiology of malaria. Micro-geographic heterogeneity of malaria infection could have implications for designing targ[...]![]()
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Background: Most analyses of gaps in human resources for health (HRH) do not consider training and the transition of graduates into the labour market. This study aims to explore the labour market for Peru's recent medical, nursing, and midwifery[...]![]()
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Seyoum, Dinberu ; Kifle, Yehenew-Getachew ; Rondeau, Virginie ; Yewhalaw, Delenasaw ; Duchateau, Luc ; Rosas-Aguirre, Angel ; Speybroeck, Niko | BMC | 2019-02-06T14:45:59ZBACKGROUND: The identification of epidemiological pattern of infection with Plasmodium falciparum and Plasmodium vivax in malaria-endemic area, where multiple episodes are common, is important for intervention programmes. METHODS: A longitudina[...]![]()
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Lazo-Porras, Maria ; Bernabé-Ortiz, Antonio ; Sacksteder, Katherine A. ; Gilman, Robert H. ; Malaga, German ; Armstrong, David G. ; Miranda, J. Jaime | BMC | 2019-02-06T14:51:21ZBACKGROUND: Diabetic foot neuropathy (DFN) is one of the most important complications of diabetes mellitus; its early diagnosis and intervention can prevent foot ulcers and the need for amputation. Thermometry, measuring the temperature of the f[...]![]()
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Shah, Lena ; Rojas, Marlene ; Mori, Oscar ; Zamudio, Carlos ; Kaufman, Jay S. ; Otero, Larissa ; Gotuzzo, Eduardo ; Seas, Carlos ; Brewer, Timothy F. | BMC | 2019-02-06T14:59:05ZBACKGROUND: We designed a pragmatic stepped-wedge cluster randomized controlled trial in order to evaluate provider-initiated evaluation of household contacts (HCs) of smear positive tuberculosis (TB) cases within a routine TB program in Lima, P[...]![]()
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Moreno, Marta ; Saavedra, Marlon P. ; Bickersmith, Sara A. ; Lainhart, William ; Tong, Carlos ; Alava, Freddy ; Vinetz, Joseph M. ; Conn, Jan E. | BMC | 2019-02-06T14:53:06ZBACKGROUND: Malaria transmission in the peri-Iquitos region of Amazonian Peru has been designated as seasonal and hypo-endemic with recently described hyper-endemic hotspots. Despite relatively recent distribution of long-lasting insecticidal be[...]![]()
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Escombe, A.R. ; Ticona, E. ; Chávez-Pérez, V. ; Espinoza, M. ; Moore, D.A.J. | BMC | 2019-12-06T21:02:55ZBackground: TB transmission in healthcare facilities is an important public health problem, especially in the often-overcrowded settings of HIV treatment scale-up. The problem is compounded by the emergence of drug resistant TB. Natural ventilat[...]![]()
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Escombe, A.R. ; Ticona, E. ; Chávez-Pérez, V. ; Espinoza, M. ; Moore, D.A.J. | BMC | 2019-07-04T17:00:16ZBackground: TB transmission in healthcare facilities is an important public health problem, especially in the often-overcrowded settings of HIV treatment scale-up. The problem is compounded by the emergence of drug resistant TB. Natural ventilat[...]![]()
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Kephart, Josiah L. ; Fandiño-Del-Rio, Magdalena ; Koehler, Kirsten ; Bernabé-Ortiz, Antonio ; Miranda, J. Jaime ; Gilman, Robert H. ; Checkley, William | BMC | 2020-07-14T00:02:29ZBACKGROUND: Indoor air pollution is an important risk factor for health in low- and middle-income countries. METHODS: We measured indoor fine particulate matter (PM2.5) and carbon monoxide (CO) concentrations in 617 houses across four settings w[...]![]()
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Torres-Sánchez, María ; Wilkinson, Mark ; Gower, David J. ; Creevey, Christopher J. ; San Mauro, Diego | BMC | 2020-07-27Background: Gene expression profiles can provide insights into the molecular machinery behind tissue functions and, in turn, can further our understanding of environmental responses, and developmental and evolutionary processes. During vertebrat[...]![]()
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Abstract Background Voluntary Counseling and Testing (VCT) is an HIV prevention strategy that promotes the principles of confidentiality and informed consent. International research has highlighted VCT counselors’ isolation from service planning[...]![]()
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Guillen, Miguel A. ; Mejia, Fernando A. ; Villena, Jaime ; Turin, Christie G. ; Carcamo, Cesar P. ; Ticse, Ray | BMC | 2019-02-06T14:52:18ZBACKGROUND: The highly active antiretroviral therapy (HAART) has altered the course of HIV infection, transforming it from a fatal illness to a chronic condition, reducing morbidity and mortality. However, this therapy has led to an increased i[...]![]()
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Ahijado Guzmán, Rubén ; Sánchez Arribas, Natalia ; Martínez Negro, María ; González Rubio, Guillermo ; Santiago-Varela, María ; Pardo, María ; Piñeiro, Antonio ; López-Montero, Iván ; Junquera González, Elena ; Guerrero Martínez, Andrés | BMC | 2020-03-11Efficient plasmonic photothermal therapies (PPTTs) using non-harmful pulse laser irradiation at the near-infrared (NIR) are a highly sought goal in nanomedicine. These therapies rely on the use of plasmonic nanostructures to kill cancer cells wh[...]![]()
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Warren, Joshua L. ; Grandjean, Louis ; Moore, David A. J. ; Lithgow, Anna ; Coronel, Jorge ; Sheen, Patricia ; Zelner, Jonathan L. ; Andrews, Jason R. ; Cohen, Ted | BMC | 2018-11-30T17:17:14ZBACKGROUND: Congregate settings may serve as institutional amplifiers of tuberculosis (TB) and multidrug-resistant tuberculosis (MDR-TB). We analyze spatial, epidemiological, and pathogen genetic data prospectively collected from neighborhoods s[...]![]()
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Merino, Veronika ; Westgard, Christopher M. ; Bayer, Angela M. ; García, Patricia J. | BMC | 2019-01-25T15:28:04ZBACKGROUND: The parasitic disease, cystic echinococcosis (CE), is prevalent in low-income, livestock-raising communities and 2000 new people will be diagnosed this year in South America alone. The disease usually passes from livestock to dogs to[...]![]()
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Abstract Background New technologies facilitate the enhancement of a wide range of human dispositions, capacities, or abilities. While it is argued that we need to set limits to human enhancement, it is unclear where we should find resources to [...]![]()
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de la Fuente Herreruela, Diego ; Monnappa, Ajay K. ; Muñoz Úbeda, Mónica ; Morallón Piña, Aarón ; Enciso Rodríguez, Eduardo ; Sánchez Martín, Luis ; Giusti, Fabrice ; Natale, Paolo ; López-Montero, Iván | BMC | 2019Background: The design of efcient drug delivery vectors requires versatile formulations able to simultaneously direct a multitude of molecular targets and to bypass the endosomal recycling pathway of cells. Liposomal-based vectors need the decor[...]![]()
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Cobos Muñoz, Daniel ; Hansen, Kristian Schultz ; Terris-Prestholt, Fern ; Cianci, Fiona ; Perez-Lu, Jose Enrique ; Lama, Aldo ; García, Patricia J. | BMC | 2019-02-06T14:52:17ZBACKGROUND: Prepaid contributory systems are increasingly being recognized as key mechanisms in achieving universal health coverage in low and middle-income countries. Peru created the Seguro Integral de Salud (SIS) to increase health service us[...]![]()
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Felisbino-Mendes, M.S. ; Matozinhos, F.P. ; Miranda, J.J. ; Villamor, E. ; Velasquez-Melendez, G. | BMC | 2020-06-10T18:11:31ZBackground: Obesity is highly related to negative reproductive health outcomes, but its relationship with spontaneous abortion and stillbirth remains to be understood, especially in transitioning economies. This study aimed to examine the relati[...]![]()
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Rosas-Aguirre, Angel ; Guzmán-Guzmán, Mitchel ; Gamboa, Dionicia ; Chuquiyauri, Raúl ; Ramirez, Roberson ; Manrique, Paulo ; Carrasco-Escobar, Gabriel ; Puemape, Carmen ; Llanos-Cuentas, Alejandro ; Vinetz, Joseph M. | BMC | 2019-01-25T15:28:05ZBACKGROUND: Understanding the dynamics of malaria transmission in diverse endemic settings is key for designing and implementing locally adapted and sustainable control and elimination strategies. A parasitological and epidemiological survey was[...]![]()
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Campos, Melina ; Conn, Jan E. ; Alonso, Diego Peres ; Vinetz, Joseph M. ; Emerson, Kevin J. ; Ribolla, Paulo Eduardo Martins | BMC | 2019-01-25T15:28:05ZBACKGROUND: In recent decades, throughout the Amazon Basin, landscape modification contributing to profound ecological change has proceeded at an unprecedented rate. Deforestation that accompanies human activities can significantly change aspect[...]![]()
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Grajeda, Laura M. ; Ivanescu, Andrada ; Saito, Mayuko ; Crainiceanu, Ciprian ; Jaganath, Devan ; Gilman, Robert H. ; Crabtree, Jean E. ; Kelleher, Dermott ; Cabrera, Lilia ; Cama, Vitaliano ; Checkley, William | BMC | 2019-02-06T14:45:34ZBACKGROUND: Childhood growth is a cornerstone of pediatric research. Statistical models need to consider individual trajectories to adequately describe growth outcomes. Specifically, well-defined longitudinal models are essential to characteriz[...]![]()
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Rosas-Aguirre, Angel ; Erhart, Annette ; Llanos-Cuentas, Alejandro ; Branch, Oralee ; Berkvens, Dirk ; Abatih, Emmanuel ; Lambert, Philippe ; Frasso, Gianluca ; Rodriguez, Hugo ; Gamboa, Dionicia ; Sihuincha, Moises ; Rosanas-Urgell, Anna ; D'Alessandro, Umberto ; Speybroeck, Niko | BMC | 2019-02-06T14:53:08ZBACKGROUND: Focal screening and treatment (FSAT) of malaria infections has recently been introduced in Peru to overcome the inherent limitations of passive case detection (PCD) and further decrease the malaria burden. Here, we used a relatively[...]![]()
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Del Valle-Mendoza, Juana ; Rojas-Jaimes, Jesus ; Vásquez-Achaya, Fernando ; Aguilar-Luis, Miguel Angel ; Correa-Nuñez, Germán ; Silva-Caso, Wilmer ; Lescano, Andres G. ; Song, Xiuping ; Liu, Qiyong ; Li, Dongmei | BMC | 2018-12-03T17:02:46ZOBJECTIVE: To study the presence of Bartonella bacilliformis in ticks collected from two wild mammals in Madre de Dios, Peru. RESULTS: A total of 110 ticks were collected. Among the 43 Amblyomma spp. extracted from the 3 Tapirus terrestris only [...]![]()
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Abstract
Background
Nigeria is home to more people living with HIV than any other country in the world, except South Africa and India – where an estimated 2.9 million [1.7 million – 4.2 million] people were living with the virus[...]
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Sheen, Patricia ; Requena, David ; Gushiken, Eduardo ; Gilman, Robert H. ; Antiparra, Ricardo ; Lucero, Bryan ; Lizárraga, Pilar ; Cieza, Basilio ; Roncal, Elisa ; Grandjean, Louis ; Pain, Arnab ; McNerney, Ruth ; Clark, Taane G. ; Moore, David ; Zimic, Mirko | BMC | 2019-01-25T15:02:14ZBACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the efforts to control this disease. Pyrazinamide (PZA) is an important drug used in both first and second line treatment regimes. However, its comple[...]![]()
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Herranz, María ; Leander, Brian S. ; Pardos Martínez, Fernando ; Boyle, Michael J. | BMC | 2019-04-08Background The Scalidophora (Kinorhyncha, Loricifera and Priapulida) have an important phylogenetic position as early branching ecdysozoans, yet the architecture of their nervous organ systems is notably underinvestigated. Without such informati[...]![]()
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Guevara, Govinda ; Castillo López, María ; Alonso, Sergio ; Perera González, Julián ; Navarro LLorens, Juana María | BMC | 2019Background: Rhodococcus ruber strain Chol-4, a strain isolated from a sewage sludge sample, is able to grow in minimal medium supplemented with several compounds, showing a broad catabolic capacity. We have previously determined its genome seque[...]![]()
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Castro, Juan C. ; Maddox, J. Dylan ; Cobos, Marianela ; Requena, David ; Zimic, Mirko ; Bombarely, Aureliano ; Iman, Sixto A. ; Cerdeira, Luis A. ; Medina, Andersson E. | BMC | 2019-02-06T14:52:14ZBackground. Myrciaria dubia is an Amazonian fruit shrub that produces numerous bioactive phytochemicals, but is best known by its high L-ascorbic acid (AsA) content in fruits. Pronounced variation in AsA content has been observed both within and[...]![]()
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Aguareles, José ; Paraíso Luna, Juan ; Palomares, Belén ; Bajo-Grañeras, Raquel ; Navarrete, Carmen ; Ruiz-Calvo, Andrea ; García Rincón, Daniel ; García-Taboada, Elena ; Guzmán, Manuel ; Muñoz, Eduardo ; Galve Roperh, Ismael | BMC | 2019-03-08Background: The administration of certain cannabinoids provides neuroprotection in models of neurodegenerative diseases by acting through various cellular and molecular mechanisms. Many cannabinoid actions in the nervous system are mediated by C[...]![]()
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Gaewkhiew, Piyada ; Bernabe, Eduardo ; Gallagher, Jennifer E. ; Klass, Charlotte ; Delgado-Angulo, Elsa K. | BMC | 2019-01-25T15:28:07ZBACKGROUND: Dental care seeking behaviour is often driven by symptoms. The value of oral health related quality of life (OHRQoL) measures to predict utilisation of dental services is unknown. This study aims to explore the association between OH[...]![]()
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DeMiguel, Daniel ; Domingo Martínez, Laura ; Sánchez, Israel M. ; Casanovas Vilar, Isaac ; Robles, Josep M. ; Alba, David M. | BMC | 2021Background The two main primate groups recorded throughout the European Miocene, hominoids and pliopithecoids, seldom co-occur. Due to both their rarity and insufficiently understood palaeoecology, it is currently unclear whether the infrequent[...]![]()
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Plaza-GA, Ismael ; Manzaneda González, Vanesa ; Kisovec, Matic ; Almendro Vedia, Víctor ; Muñoz Úbeda, Mónica ; Anderluh, Gregor ; Guerrero Martínez, Andrés ; Natale, Paolo ; López-Montero, Iván | BMC | 2019Background: A major bottleneck in drug delivery is the breakdown and degradation of the delivery system through the endosomal/lysosomal network of the host cell, hampering the correct delivery of the drug of interest. In nature, the bacterial pa[...]![]()
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Werneck, Andre O. ; Baldew, Se-Sergio ; Miranda, J. Jaime ; Diaz Arnesto, Oscar ; Stubbs, Brendon ; Silva, Danilo R. | BMC | 2019-12-06T20:57:38ZBACKGROUND: Physical inactivity and sedentary behavior are major concerns for public health. Although global initiatives have been successful in monitoring physical activity (PA) worldwide, there is no systematic action for the monitoring of cor[...]![]()
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Rosas-Aguirre, Angel ; Ponce, Oscar J. ; Carrasco-Escobar, Gabriel ; Speybroeck, Niko ; Contreras-Mancilla, Juan ; Gamboa, Dionicia ; Pozo, Edwar ; Herrera, Socrates ; Llanos-Cuentas, Alejandro | BMC | 2019-02-06T14:53:06ZBACKGROUND: Peru has presented a decreasing malaria trend during the last decade, particularly in areas on northwestern coast; however, a limited number of cases continues to be reported yearly mainly in malaria hotspots. METHODS: A two-phase s[...]![]()
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Delgado-Ratto, C. ; Soto-Calle, V.E. ; Van Den Eede, P. ; Gamboa, D. ; Rosas, A. ; Abatih, E.N. ; Rodriguez Ferrucci, H. ; Llanos-Cuentas, A. ; Van Geertruyden, J.-P. ; Erhart, A. ; D'Alessandro, U. | BMC | 2020-06-10T18:12:15ZBackground: Despite the large burden of Plasmodium vivax, little is known about its transmission dynamics. This study explored the population structure and spatio-temporal dynamics of P. vivax recurrent infections after radical cure in a two-yea[...]![]()
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Zafra-Tanaka, Jessica Hanae ; Montesinos-Segura, Renee ; Flores-Gonzales, Pamela D. ; Taype-Rondan, Álvaro | BMC | 2019-12-06T21:02:53ZBACKGROUND: A high number of vaginal examinations (VEs) may lead to a higher risk of infections, as well as discomfort/dissatisfaction with intrapartum care. OBJECTIVE: To determine the frequency of potential excess of vaginal examinations (PEVE[...]![]()
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Bayer, Angela M. ; Najarro, Lizzete ; Zevallos, Mercedes ; García, Patricia J. | BMC | 2020-06-10T18:12:16ZBACKGROUND: Globally, no qualitative studies have explored the perspectives of women and their partners about the integration of technology - and specifically diagnostic testing technologies - into antenatal care. The study objective was to desc[...]![]()
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Herrera-Añazco, Percy ; Taype-Rondan, Álvaro ; Lazo-Porras, Maria ; Alberto Quintanilla, E. ; Ortiz-Soriano, Victor Manuel ; Hernandez, Adrian V. | BMC | 2019-01-25T15:28:08ZBACKGROUND: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in p[...]![]()
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Jaganath, Devan ; Miranda, J. Jaime ; Gilman, Robert H. ; Wise, Robert A. ; Diette, Gregory B. ; Miele, Catherine H. ; Bernabé-Ortiz, Antonio ; Checkley, William | BMC | 2019-02-06T14:53:35ZBACKGROUND: It is unclear how geographic and social diversity affects the prevalence of chronic obstructive pulmonary disease (COPD). We sought to characterize the prevalence of COPD and identify risk factors across four settings in Peru with va[...]![]()
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Abstract Background Treatment and special protection of the rights of incarcerated young people in prisons are mandated under the Sustainable Development Goals (SDG), as well as under United Nations (UN) human rights instruments. Methods A scopi[...]![]()
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Limbani, Felix ; Goudge, Jane ; Joshi, Rohina ; Maar, Marion A. ; Miranda, J. Jaime ; Oldenburg, Brian ; Parker, Gary ; Pesantes, María Amalia ; Riddell, Michaela A. ; Salam, Abdul ; Trieu, Kathy ; Thrift, Amanda G. ; Van Olmen, Josefien ; Vedanthan, Rajesh ; Webster, Ruth ; Yeates, Karen ; Webster, Jacqui | BMC | 2019-12-06T20:57:42ZBACKGROUND: Process evaluation is increasingly recognized as an important component of effective implementation research and yet, there has been surprisingly little work to understand what constitutes best practice. Researchers use different met[...]![]()
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Limbani, Felix ; Goudge, Jane ; Joshi, Rohina ; Maar, Marion A. ; Miranda, J. Jaime ; Oldenburg, Brian ; Parker, Gary ; Pesantes, María Amalia ; Riddell, Michaela A. ; Salam, Abdul ; Trieu, Kathy ; Thrift, Amanda G. ; Van Olmen, Josefien ; Vedanthan, Rajesh ; Webster, Ruth ; Yeates, Karen ; Webster, Jacqui | BMC | 2019-08-08T15:23:44ZBACKGROUND: Process evaluation is increasingly recognized as an important component of effective implementation research and yet, there has been surprisingly little work to understand what constitutes best practice. Researchers use different met[...]![]()
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Otero, Larissa ; Shah, Lena ; Verdonck, Kristien ; Battaglioli, Tullia ; Brewer, Timothy ; Gotuzzo, Eduardo ; Seas, Carlos ; Van-der-Stuyft, Patrick | BMC | 2019-02-06T14:45:56ZBACKGROUND: Household contacts (HHCs) of TB cases are at increased risk for TB disease compared to the general population but the risk may be modified by individual or household factors. We conducted a study to determine incident TB among HHCs o[...]![]()
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Gonsalves, Lianne ; Hindin, Michelle J. ; Bayer, Angela ; Carcamo, Cesar P. ; Gichangi, Peter ; Habib, Ndema ; Mwaisaka, Jefferson ; Say, Lale | BMC | 2018-11-30T22:50:36ZBACKGROUND: Young people face special challenges to accessing needed sexual and reproductive health (SRH) information and support. With high penetration and access, mobile phones provide a new channel for reaching young people, but there is litt[...]![]()
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Background: Many of the assessment tools used to study depression among older people are adaptations of instruments developed in other cultural setting. There is a need to validate those instruments in low and middle income countries (LMIC). Met[...]![]()
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Gómez-Restrepo, Carlos ; Maldonado, Patricia ; Rodríguez, Nelcy ; Ruiz-Gaviria, Rafael ; Escalante, Miguel Ángel ; Gómez, Raúl Ángel ; Ribeiro-de-Araujo, Marcelo ; Schmidt-de-Oliveira, Ana Carolina ; Chávez-Rivera, Joel Salvador ; Godínez-García, Jorge Alberto ; Piazza-Ferrand, Marina ; Blitchtein-Winicki, Dora | BMC | 2019-01-25T16:03:19ZBACKGROUND: In Latin America, substance related disorders are highly prevalent and one of the treatment strategies is the Therapeutic Communities (TCs), however, in Latin America there is scarce data about this treatment strategies, their qualit[...]![]()
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Martiáñez-Vendrell, Xavier ; Jimenez, Alfons ; Vásquez, Ana ; Campillo, Ana ; Incardona, Sandra ; González, Raquel ; Gamboa, Dionicia ; Torres, Katherine ; Oyibo, Wellington ; Faye, Babacar ; Macete, Eusebio ; Menéndez, Clara ; Ding, Xavier C. ; Mayor, Alfredo | BMC | 2020-07-14T00:02:33ZBACKGROUND: Malaria diagnostics by rapid diagnostic test (RDT) relies primarily on the qualitative detection of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and Plasmodium spp lactate dehydrogenase (pLDH). As novel RDTs with increased[...]![]()
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Martin, Laura J. ; Roper, Martha H. ; Grandjean, Louis ; Gilman, Robert H. ; Coronel, Jorge ; Caviedes, Luz ; Friedland, Jon S. ; Moore, David A. J. | BMC | 2019-02-06T14:45:55ZBACKGROUND: Early identification of patients with drug-resistant tuberculosis (DR-TB) increases the likelihood of treatment success and interrupts transmission. Resource-constrained settings use risk profiling to ration the use of drug suscepti[...]![]()
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Phelan, Jody-E. ; Coll, Francesc ; Bergval, Indra ; Anthony, Richard-M. ; Warren, Rob ; Sampson, Samantha-L. ; Gey-van-Pittius, Nicolaas-C. ; Glynn, Judith-R. ; Crampin, Amelia-C. ; Alves, Adriana ; Bessa, Theolis-Barbosa ; Campino, Susana ; Dheda, Keertan ; Grandjean, Louis ; Hasan, Rumina ; Hasan, Zahra ; Miranda, Anabela ; Moore, David ; Panaiotov, Stefan ; Perdigão, João ; Portugal, Isabel ; Sheen, Patricia ; de-Oliveira-Sousa, Erivelton ; Streicher, Elizabeth-M. ; van-Helden, Paul-D. ; Viveiros, Miguel ; Hibberd, Martin-L. ; Pain, Arnab ; McNerney, Ruth ; Clark, Taane-G. | BMC | 2019-02-06T14:45:57ZBACKGROUND: Approximately 10% of the Mycobacterium tuberculosis genome is made up of two families of genes that are poorly characterized due to their high GC content and highly repetitive nature. The PE and PPE families are typified by their hig[...]![]()
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Torres, K.J. ; Villasis, E. ; Bendezú, J. ; Chauca, J. ; Vinetz, J.M. ; Gamboa, D. | BMC | 2020-06-10T18:12:15ZBackground: Previous data have suggested that regulatory T cells (Tregs) balance protective immune responses with immune mediated pathology in malaria. This study aimed to determine to test the hypothesis that Treg proportions or absolute levels[...]![]()
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Tam, Yvonne ; Huicho, Luis ; Huayanay-Espinoza, Carlos-A. ; Restrepo-Mendez, Maria-Clara | BMC | 2019-02-06T14:48:07ZBACKGROUND: Peru has made great improvements in reducing stunting and child mortality in the past decade, and has reached the Millennium Development Goals 1 and 4. The remaining challenges or missed opportunities for child survival needs to be[...]![]()
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McFarland, Adam P. ; Sanchez, Juan F. ; Mercado, Alejandro ; Ventocilla, Julio A. ; Cavalcanti, Sofia ; Gonzalez, Sofia ; Lescano, Andres G. | BMC | 2019-02-06T14:59:07ZTwo Plasmodium vivax recurrences in a Peruvian sailor with weight above the 60 kg (cap for primaquine dosage) highlight the importance of adequate radical cure weight dosage for patient treatment and control efforts, particularly within the mil[...]![]()
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Carrillo-Larco, Rodrigo M. ; Miranda, J. Jaime ; Gilman, Robert H. ; Medina-Lezama, Josefina ; Chirinos-Pacheco, Julio A. ; Muñoz-Retamozo, Paola V. ; Smeeth, Liam ; Checkley, William ; Bernabé-Ortiz, Antonio ; CRONICAS Cohort Study Group | BMC | 2019-01-25T16:03:19ZBACKGROUND: Chronic Kidney Disease (CKD) represents a great burden for the patient and the health system, particularly if diagnosed at late stages. Consequently, tools to identify patients at high risk of having CKD are needed, particularly in l[...]![]()
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Abstract Recent years have seen contentious debate about efforts to schedule medicines such as ketamine and tramadol under the international drug control conventions. Proponents argue that misuse poses a significant risk to public health and tha[...]![]()
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Zammarchi, Lorenzo ; Casadei, Gianluigi ; Strohmeyer, Marianne ; Bartalesi, Filippo ; Liendo, Carola ; Matteelli, Alberto ; Bonati, Maurizio ; Gotuzzo, Eduardo ; Bartoloni, Alessandro | BMC | 2019-02-06T14:52:14ZBACKGROUND: In low-incidence countries, most tuberculosis (TB) cases occur among migrants and are caused by reactivation of latent tuberculosis infection (LTBI) acquired in the country of origin. Diagnosis and treatment of LTBI are rarely imple[...]![]()
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Pray, Ian W. ; Muro, Claudio ; Gamboa, Ricardo ; Vilchez, Percy ; Wakeland, Wayne ; Pan, William ; Lambert, William E. ; Garcia, Hector H. ; O'Neal, Seth E. | BMC | 2019-12-06T20:57:42ZBACKGROUND: Taenia solium (cysticercosis) is a parasitic cestode that is endemic in rural populations where open defecation is common and free-roaming pigs have access to human feces. The purpose of this study was to examine the roaming pattern[...]![]()
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Pray, Ian W. ; Muro, Claudio ; Gamboa, Ricardo ; Vilchez, Percy ; Wakeland, Wayne ; Pan, William ; Lambert, William E. ; Garcia, Hector H. ; O'Neal, Seth E. | BMC | 2019-08-08T15:23:47ZBACKGROUND: Taenia solium (cysticercosis) is a parasitic cestode that is endemic in rural populations where open defecation is common and free-roaming pigs have access to human feces. The purpose of this study was to examine the roaming pattern[...]![]()
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Bui, A.L. ; Moscoso, M.G. ; Bernabé-Ortiz, A. ; Checkley, W. ; Gilman, R.H. ; Smeeth, L. ; Miranda, J.J. | BMC | 2019-12-06T20:57:47ZBackground: Individuals' self-perceptions of weight often differ from objective measurements of body fat. This study aimed to 1) measure agreement between self-perceptions of weight and objective measurement of body fat by bioelectric impedance [...]![]()
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Bui, Anthony L. ; Moscoso, Miguel G. ; Bernabé-Ortiz, Antonio ; Checkley, William ; Gilman, Robert H. ; Smeeth, Liam ; Miranda, J. Jaime | BMC | 2019-07-04T16:59:17ZBackground: Individuals' self-perceptions of weight often differ from objective measurements of body fat. This study aimed to 1) measure agreement between self-perceptions of weight and objective measurement of body fat by bioelectric impedance [...]![]()
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Aragon, Romina E. ; Proaño, Alvaro ; Mongilardi, Nicole ; de Ferrari, Aldo ; Herrera, Phabiola ; Roldan, Rollin ; Paz, Enrique ; Jaymez, Amador A. ; Chirinos, Eduardo ; Portugal, Jose ; Quispe, Rocio ; Brower, Roy G. ; Checkley, William | BMC | 2019-07-04T17:00:23ZOBJECTIVES: We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting. DESIGN: A longitudinal study of critically ill participants [...]![]()
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Aragón, R.E. ; Proaño, A. ; Mongilardi, N. ; de Ferrari, A. ; Herrera, P. ; Roldan, R. ; Paz, E. ; Jaymez, A.A. ; Chirinos, E. ; Portugal, J. ; Quispe, R. ; Brower, R.G. ; Checkley, W. | BMC | 2019-12-06T20:57:46ZObjectives: We sought to study the association between sedation status, medications (benzodiazepines, opioids, and antipsychotics), and clinical outcomes in a resource-limited setting. Design: A longitudinal study of critically ill participants [...]![]()
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BACKGROUND: One of the keys to improving health globally is promoting mothers' adoption of healthy home practices for improved nutrition and illness prevention in the first 1000 days of life from conception. Customarily, mothers are taught healt[...]![]()
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Jensen, Kelly E. ; Naik, Nehal N. ; O'Neal, Christina ; Salmón-Mulanovich, Gabriela ; Riley-Powell, Amy R. ; Lee, Gwenyth O. ; Hartinger, Stella M. ; Bausch, Daniel G. ; Paz-Soldan, Valerie A. | BMC | 2018-11-30T22:50:37ZBACKGROUND: Madre de Dios, a southern state in the Peruvian Amazon basin, has experienced rapid development as well as an influx of migrants since the construction of the Interoceanic Highway (IOH) connecting Brazil, Bolivia, and the Peruvian co[...]![]()
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Taype-Rondan, Álvaro ; Bernabé-Ortiz, Antonio ; Alvarado, German F. ; Gilman, Robert H. ; Smeeth, Liam ; Miranda, J. Jaime | BMC | 2019-01-25T16:03:20ZBACKGROUND: Previous studies have found mixed results about cigarette and alcohol consumption patterns among rural-to-urban migrants. Moreover, there are limited longitudinal data about consumption patterns in this population. As such, this stud[...]![]()
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Background: Ethnic inequalities in oral health among British adults remain largely unexplored. This study explored the role of socioeconomic position (SEP) in explaining ethnic inequalities in oral health; and the consistency of socioeconomic in[...]![]()
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BACKGROUND: Ethnic inequalities in oral health among British adults remain largely unexplored. This study explored the role of socioeconomic position (SEP) in explaining ethnic inequalities in oral health; and the consistency of socioeconomic i[...]![]()
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Carrasco-Escobar, Gabriel ; Schwalb, Alvaro ; Tello-Lizarraga, Kelly ; Vega-Guerovich, Percy ; Ugarte-Gil, Cesar | BMC | 2020-07-14T00:01:00ZGrowing evidence suggests pollution and other environmental factors have a role in the development of tuberculosis (TB), however, such studies have never been conducted in Peru. Considering the association between air pollution and specific geog[...]![]()
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Akpan, Asangaedem ; Roberts, Charlotte ; Bandeen-Roche, Karen ; Batty, Barbara ; Bausewein, Claudia ; Bell, Diane ; Bramley, David ; Bynum, Julie ; Cameron, Ian D. ; Chen, Liang-Kung ; Ekdahl, Anne ; Fertig, Arnold ; Gentry, Tom ; Harkes, Marleen ; Haslehurst, Donna ; Hope, Jonathon ; Hurtado, Diana Rodriguez ; Lyndon, Helen ; Lynn, Joanne ; Martin, Mike ; Isden, Ruthe ; Raso, Francesco Mattace ; Shaibu, Sheila ; Shand, Jenny ; Sherrington, Cathie ; Sinha, Samir ; Turner, Gill ; De Vries, Nienke ; Yi, George Jia-Chyi ; Young, John ; Banerjee, Jay | BMC | 2018-11-30T22:50:37ZBACKGROUND: The International Consortium for Health Outcomes Measurement (ICHOM) was founded in 2012 to propose consensus-based measurement tools and documentation for different conditions and populations.This article describes how the ICHOM Old[...]![]()
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Vasquez-Rios, George ; Pineda-Reyes, Roberto ; Ruiz, Eloy F. ; Terashima, Angélica ; Mejia, Fernando | BMC | 2019-07-04T17:01:20ZBACKGROUND: In clinical practice, identification of a case of severe asthma exacerbation prompts initiation of corticosteroids. However, not all that wheezes is asthma. CASE PRESENTATION: A 61-year-old man from the Peruvian Amazon presented with[...]![]()
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Vasquez-Rios, G. ; Pineda-Reyes, R. ; Ruiz, E.F. ; Terashima, A. ; Mejia, F. | BMC | 2019-12-06T20:57:50ZBackground: In clinical practice, identification of a case of severe asthma exacerbation prompts initiation of corticosteroids. However, not all that wheezes is asthma. Case presentation: A 61-year-old man from the Peruvian Amazon presented with[...]![]()
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St-Jean, Pamela-L. ; Xue, Zhengyu ; Carter, Nick ; Koh, Gavin-C. K. W. ; Duparc, Stephan ; Taylor, Maxine ; Beaumont, Claire ; Llanos-Cuentas, Alejandro ; Rueangweerayut, Ronnatrai ; Krudsood, Srivicha ; Green, Justin-A. ; Rubio, Justin-P. | BMC | 2019-02-06T14:48:06ZBACKGROUND: Tafenoquine (TQ) and primaquine (PQ) are 8-aminoquinolines (8-AQ) with anti-hypnozoite activity against vivax malaria. PQ is the only FDA-approved medicine for preventing relapsing Plasmodium vivax infection and TQ is currently in [...]![]()
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Cardenas, Maria Kathia ; Mirelman, Andrew J. ; Galvin, Cooper J. ; Lazo-Porras, Maria ; Pinto, Miguel ; Miranda, J. Jaime ; Gilman, Robert H. | BMC | 2019-02-06T14:52:14ZBACKGROUND: Diabetes mellitus is a public health challenge worldwide, and roughly 25% of patients with diabetes in developing countries will develop at least one foot ulcer during their lifetime. The gravest outcome of an ulcerated foot is amput[...]![]()
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Stein, D. J. ; Lim, C. C. W. ; Roest, A. M. ; de Jonge, P. ; Aguilar-Gaxiola, S. ; Al-Hamzawi, A. ; Alonso, J. ; Benjet, C. ; Bromet, E. J. ; Bruffaerts, R. ; de Girolamo, G. ; Florescu, S. ; Gureje, O. ; Haro, J. M. ; Harris, M. G. ; He, Y. L. ; Hinkov, H. ; Horiguchi, I. ; Hu, C. Y. ; Karam, A. ; Karam, E. G. ; Lee, S. ; Lepine, J. P. ; Navarro-Mateu, F. ; Pennell, B. E. ; Piazza, M. ; Posada-Villa, J. ; ten Have, M. ; Torres, Y. ; Viana, M. C. ; Wojtyniak, B. ; Xavier, M. ; Kessler, R. C. ; Scott, K. M. ; WHO World Mental Health Survey | BMC | 2019-01-25T16:20:58ZBackground: There is evidence that social anxiety disorder (SAD) is a prevalent and disabling disorder. However, most of the available data on the epidemiology of this condition originate from high income countries in the West. The World Mental [...]![]()
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Di Cesare, Mariachiara ; Soric, Maroje ; Bovet, Pascal ; Miranda, J. Jaime ; Bhutta, Zulfiqar ; Stevens, Gretchen A. ; Laxmaiah, Avula ; Kengne, Andre-Pascal ; Bentham, James | BMC | 2019-12-06T20:57:49ZBACKGROUND: In recent decades, the prevalence of obesity in children has increased dramatically. This worldwide epidemic has important consequences, including psychiatric, psychological and psychosocial disorders in childhood and increased risk[...]![]()
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Background: Tobacco exposure remains a significant issue for public health, especially for pregnant women. It increases the risk for premature labor, low birth weight and small for gestational age (SGA), among other effects. To reduce these risk[...]![]()
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Kojima, Noah ; Park, Hayoung ; Konda, Kelika A. ; Joseph Davey, Dvora L. ; Bristow, Claire C. ; Brown, Brandon ; Leon, Segundo R. ; Vargas, Silver K. ; Calvo, Gino M. ; Caceres, Carlos F. ; Klausner, Jeffrey D. | BMC | 2019-01-25T16:03:22ZBACKGROUND: Men who have sex with men (MSM) and male-to-female transgender women (transwomen) are disproportionately at risk of syphilis infection in Peru. METHODS: From 2013 to 2014, MSM and transwomen seeking human immunodeficiency virus (HIV)[...]![]()
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Wolfson, Lara J. ; Castillo, Maria Esther ; Giglio, Norberto ; Meszner, Zsofia ; Molnar, Zsuzsanna ; Vazquez, Mirella ; Wysocki, Jacek ; Altland, Alexandra ; Kuter, Barbara J. ; Stutz, Melissa ; Rampakakis, Emmanouil ; Roberts, Craig S. | BMC | 2019-12-06T20:57:48ZBACKGROUND: Varicella is a highly contagious childhood disease. Generally benign, serious complications necessitating antibiotic use may occur. The objective of this study was to characterize the rate, appropriateness and patterns of real-world [...]![]()
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Wolfson, Lara J. ; Castillo, Maria Esther ; Giglio, Norberto ; Meszner, Zsofia ; Molnar, Zsuzsanna ; Vazquez, Mirella ; Wysocki, Jacek ; Altland, Alexandra ; Kuter, Barbara J. ; Stutz, Melissa ; Rampakakis, Emmanouil ; Roberts, Craig S. | BMC | 2019-08-08T15:23:44ZBACKGROUND: Varicella is a highly contagious childhood disease. Generally benign, serious complications necessitating antibiotic use may occur. The objective of this study was to characterize the rate, appropriateness and patterns of real-world [...]![]()
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Díaz del Cerro, Estefanía ; Vida, Carmen ; Martínez de Toda Cabeza, Irene ; Félix, Judith ; Fuente del Rey, Mónica de la | BMC | 2020-11-23Background: The immune system, as a homeostatic system, is an excellent marker of health and has also been proposed as an indicator of the rate of aging. The base of the age-related changes in the immune system, “immunosenescence”, is oxidative-[...]![]()
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Bazo-Alvarez, Juan-Carlos ; Peralta-Alvarez, Frank ; Bernabé-Ortiz, Antonio ; Alvarado, German-F. ; Miranda, J. Jaime | BMC | 2019-02-06T14:45:10ZBACKGROUND: Positive mental health (PMH) is much more than the absence of mental illnesses. For example, PMH explains that to be happy or resilient can drive us to live a full life, giving us a perception of well-being and robustness against e[...]![]()
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Boccia, Delia ; Pedrazzoli, Debora ; Wingfield, Tom ; Jaramillo, Ernesto ; Lonnroth, Knut ; Lewis, James ; Hargreaves, James ; Evans, Carlton-A. | BMC | 2019-02-06T14:51:17ZBACKGROUND: Cash transfer interventions are forms of social protection based on the provision of cash to vulnerable households with the aim of reduce risk, vulnerability, chronic poverty and improve human capital. Such interventions are already[...]![]()
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Miranda, J. Jaime ; Bernabé-Ortiz, Antonio ; Diez-Canseco, Francisco ; Malaga, German ; Cárdenas, María K. ; Carrillo-Larco, Rodrigo M. ; Lazo-Porras, Maria ; Moscoso-Porras, Miguel ; Pesantes, M. Amalia ; Ponce, Vilarmina ; Araya, Ricardo ; Beran, David ; Busse, Peter ; Boggio, Oscar ; Checkley, William ; García, Patricia J. ; Huicho, Luis ; Leon-Velarde, Fabiola ; Lescano, Andres G. ; Mohr, David-C. ; Pan, William ; Peiris, David ; Perel, Pablo ; Rabadan-Diehl, Cristina ; Rivera-Chira, Maria ; Sacksteder, Katherine ; Smeeth, Liam ; Trujillo, Antonio J. ; Wells, Jonathan C. K. ; Yan, Lijing-L. ; Garcia, Hector H. ; Gilman, Robert H. | BMC | 2019-02-06T14:51:22ZHuman capital requires opportunities to develop and capacity to overcome challenges, together with an enabling environment that fosters critical and disruptive innovation. Exploring such features is necessary to establish the foundation of solid[...]![]()
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Mirjam D. Rodella Sapia ; Tenzin Wangmo ; Stéphanie Dagron ; Bernice S. Elger | BMC | 2020-10-16T18:30:02ZAbstract Background When it comes to gender-based violence (GBV), migrant women and girls represent the most vulnerable group. GBV can happen at any stage of migrants’ flight and/or during the asylum process. It has severe consequences on their [...]![]()
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Huicho, Luis ; Hernandez, Patricia ; Huayanay-Espinoza, Carlos A. ; Segura, Eddy R. ; Niño de Guzman, Jessica ; Flores-Cordova, Gianfranco ; Rivera-Ch, Maria ; Friedman, Howard S. ; Berman, Peter | BMC | 2018-11-30T23:41:30ZBACKGROUND: Peru has increased substantially its domestic public expenditure in maternal and child health. Peruvian departments are heterogeneous in contextual and geographic factors, underlining the importance of disaggregated expenditure analy[...]![]()
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Pizzitutti, Francesco ; Pan, William ; Barbieri, Alisson ; Miranda, J. Jaime ; Feingold, Beth ; Guedes, Gilvan R. ; Alarcon-Valenzuela, Javiera ; Mena, Carlos F. | BMC | 2019-02-06T14:53:06ZBACKGROUND: The Amazon environment has been exposed in the last decades to radical changes that have been accompanied by a remarkable rise of both Plasmodium falciparum and Plasmodium vivax malaria. The malaria transmission process is highly inf[...]![]()
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Gelaye, B. ; Zheng, Y. N. ; Medina-Mora, M. E. ; Rondon, M. B. ; Sanchez, S. E. ; Williams, M. A. | BMC | 2019-01-25T16:20:58ZBackground: The PTSD Checklist-civilian (PCL-C) is one of the most commonly used self-report measures of PTSD symptoms, however, little is known about its validity when used in pregnancy. This study aims to evaluate the reliability and validity [...]![]()
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Kariyawasam, R. ; Mukkala, A.N. ; Lau, R. ; Valencia, B.M. ; Llanos-Cuentas, A. ; Boggild, A.K. | BMC | 2019-12-06T21:02:56ZBackground: Leishmania RNA virus-1 (LRV1) is a double-stranded RNA virus identified in 20-25% of Viannia - species endemic to Latin America, and is believed to accelerate cutaneous to mucosal leishmaniasis over time. Our objective was to quantif[...]![]()
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Kariyawasam, Ruwandi ; Mukkala, Avinash N. ; Lau, Rachel ; Valencia, Braulio M. ; Llanos-Cuentas, Alejandro ; Boggild, Andrea K. | BMC | 2019-07-04T17:01:24ZBackground: Leishmania RNA virus-1 (LRV1) is a double-stranded RNA virus identified in 20-25% of Viannia-species endemic to Latin America, and is believed to accelerate cutaneous to mucosal leishmaniasis over time. Our objective was to quantify[...]![]()
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Gianella, Camila ; Pesantes, M. Amalia ; Ugarte-Gil, Cesar ; Moore, David A. J. ; Lema, Claudia | BMC | 2019-12-06T20:57:42ZBACKGROUND: In 2014 the World Health Organization (WHO) launched the "End TB Strategy", setting new ambitious goals for elimination of tuberculosis (TB). In contrast with previous efforts to control TB, the new strategy adopted the protection an[...]![]()
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Gianella, Camila ; Pesantes, M. Amalia ; Ugarte-Gil, Cesar ; Moore, David A. J. ; Lema, Claudia | BMC | 2019-07-04T17:01:24ZBackground. In 2014 the World Health Organization (WHO) launched the “End TB Strategy”, setting new ambitious goals for elimination of tuberculosis (TB). In contrast with previous efforts to control TB, the new strategy adopted the protection an[...]![]()
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Torres-Sánchez, María ; Gower, David J. ; Álvarez-Ponce, David ; Creevey, Christopher J. ; Wilkinson, Mark ; San Mauro, Diego | BMC | 2019-05-09Background Evolution leaves an imprint in species through genetic change. At the molecular level, evolutionary changes can be explored by studying ratios of nucleotide substitutions. The interplay among molecular evolution, derived phenotypes, [...]![]()
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Najera, Hector ; Nandy, Shailen ; Carrillo-Larco, Rodrigo M. ; Miranda, J. Jaime | BMC | 2019-07-04T16:59:37ZBackground: Rural-to-urban migration is associated with increased obesity, yet it remains unknown whether this association exist, and to what extent, with other types of internal migration. Methods: We conducted a secondary analysis of the Peruv[...]![]()
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Lazo-Porras, Maria ; Prutsky, Gabriela J. ; Barrionuevo, Patricia ; Tapia, Jose Carlos ; Ugarte-Gil, Cesar ; Ponce, Oscar J. ; Acuna-Villaorduna, Ana ; Domecq, Juan Pablo ; De la Cruz-Luque, Celso ; Prokop, Larry J. ; Malaga, German | BMC | 2020-07-14T00:02:31ZBACKGROUND: To evaluate the effectiveness and safety of the World Health Organization antibiotic regimen for the treatment of paucibacillary (PB) and multibacillary (MB) leprosy compared to other available regimens. METHODS: We performed a searc[...]