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Rojas Lozano, Pilar ; Ramírez Sebastián, Ana Isabel ; Fernández Albarral, José Antonio ; López Cuenca, Inés ; García Martín, Elena Salobrar ; Cadena Santoyo, Manuel ; Elvira Hurtado, Lorena ; Salazar Corral, Juan José ; Hoz Montañana, Rosa de ; Ramirez Sebastian, Jose Manuel | Frontiers Media | 2020-09-25Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes degeneration of the lower and upper motor neurons and is the most prevalent motor neuron disease. This disease is characterized by muscle weakness, stiffness, and hyp[...]texto impreso
Gomáriz, Rosa P. ; Juarranz Moratilla, Yasmina ; Carrión Caballo, Mar ; Pérez García, Selene ; Villanueva Romero, Raúl ; González Álvaro, Isidoro ; Gutiérrez Cañas, Irene ; Lamana, Amalia ; Martínez, Carmen | Frontiers Media | 2019-10-22The axis comprised by the Vasoactive Intestinal Peptide (VIP) and its G protein-coupled receptors (GPCRs), VPAC1, and VPAC2, belong to the B1 family and signal through Gs or Gq proteins. VPAC receptors seem to preferentially interact with Gs in [...]texto impreso
Pérez Sancho, Marta ; Vela Alonso, Ana Isabel ; García Seco, Teresa ; Gottschalk, Marcelo ; Domínguez Rodríguez, Lucas ; Fernández Garayzábal, José Francisco | Frontiers Media | 2015The accuracy of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for identifying Streptococcus suis isolates obtained from pigs, wild animals, and humans was evaluated using a PCR-based identification a[...]texto impreso
Siques, P. ; Brito, J. ; Schwedhelm, E. ; Pena, E. ; León-Velarde, F. ; De La Cruz, J.J. ; Böger, R.H. ; Hannemann, J. | Frontiers Media | 2019-12-06T20:57:43ZBackground: Prolonged exposure to altitude-associated chronic hypoxia (CH) may cause high-altitude pulmonary hypertension (HAPH). Chronic intermittent hypobaric hypoxia (CIH) occurs in individuals who commute between sea level and high altitude.[...]texto impreso
Siques, Patricia ; Brito, Julio ; Schwedhelm, Edzard ; Pena, Eduardo ; Leon-Velarde, Fabiola ; De La Cruz, Juan Jose ; Boeger, Rainer H. ; Hannemann, Juliane | Frontiers Media | 2019-07-04T16:59:21ZBackground: Prolonged exposure to altitude-associated chronic hypoxia (CH) may cause high-altitude pulmonary hypertension (HAPH). Chronic intermittent hypobaric hypoxia (CIH) occurs in individuals who commute between sea level and high altitude.[...]texto impreso
Muñoz, Juan José ; García Ceca Hernández, Javier ; Montero Herradón, Sara ; Sánchez del Collado, Beatriz ; Alfaro Sánchez, David ; Zapata González, Agustín | Frontiers Media | 2018-04-03For a long time, the effects of distinct Eph tyrosine kinase receptors and their ligands, ephrins on the structure, immunophenotype, and development of thymus and their main cell components, thymocytes (T) and thymic epithelial cells (TECs), hav[...]texto impreso
Fonseca Vázquez, Begoña ; Martínez Águila, Alejandro ; Pérez de Lara, María Jesús ; Miras Portugal, María Teresa ; Gómez Villafuertes, María Rosa ; Pintor, Jesús | Frontiers Media | 2017-10-10Glaucoma is a neuropathology, often accompanied by an elevated intraocular pressure (IOP), which can lead to blindness. Since DBA/2J mice develop glaucoma, several studies of the physiopathology of glaucoma have been reported in this animal mode[...]texto impreso
Sanchez, Sofia S. ; Garcia, Hector H. ; Nicoletti, Alessandra | Frontiers Media | 2018-11-30T02:09:31ZHuman toxocariasis is one of the most prevalent helminthiases worldwide. Toxocara canis larvae can cross the blood-brain barrier leading to the neurotoxocariasis. The clinical presentation consists of a wide spectrum of neurological manifestatio[...]texto impreso
Moreno García, Nerea ; Joven Araus, Alberto ; Morona Arribas, Ruth ; Bandín Carazo, Sandra ; López Redondo, Jesús María ; González Gallegos, Agustín | Frontiers Media | 2014-08-06Many of the genes involved in brain patterning during development are highly conserved in vertebrates and similarities in their expression patterns help to recognize homologous cell types or brain regions. Among these genes, Pax6 and Pax7 are ex[...]texto impreso
García Rincón, Daniel ; Díaz Alonso, Javier ; Paraíso Luna, Juan ; Otega, Zaira ; Aguareles, José ; Salas Quiroga, Adán de ; Jou, Cristina ; Prada, Inmaculada de ; Martínez Cerdeño, Verónica ; Aronica, Eleonora ; Guzmán, Manuel ; Pérez-Jiménez, María Ángeles ; Galve Roperh, Ismael | Frontiers Media | 2019-01Alterations of the PI3K/Akt/mammalian target of rapamycin complex 1 (mTORC1) signaling pathway are causally involved in a subset of malformations of cortical development (MCDs) ranging from focal cortical dysplasia (FCD) to hemimegalencephaly an[...]texto impreso
Belda Aguilar, Ignacio ; Zarraonaindia, Iratxe ; Perisin, Matthew ; Palacios, Antonio ; Acedo, Alberto | Frontiers Media | 2017-06-02In the original article, there was an error in the Conflict of Interest statement. The correct version appears below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way.texto impreso
Veldic, M. ; Ahmed, A.T. ; Blacker, C.J. ; Geske, J.R. ; Biernacka, J.M. ; Borreggine, K.L. ; Moore, K.M. ; Prieto, M.L. ; Vande Voort, J.L. ; Croarkin, P.E. ; Hoberg, A.A. ; Kung, S. ; Alarcon, R.D. ; Keeth, N. ; Singh, B. ; Bobo, W.V. ; Frye, M.A. | Frontiers Media | 2019-12-06T20:57:50ZBackground: Pharmacogenomic testing, specifically for pharmacokinetic (PK) and pharmacodynamic (PD) genetic variation, may contribute to a better understanding of baseline genetic differences in patients seeking treatment for depression, which m[...]texto impreso
Veldic, Marin ; Ahmed, Ahmed T. ; Blacker, Caren J. ; Geske, Jennifer R. ; Biernacka, Joanna M. ; Borreggine, Kristin L. ; Moore, Katherine M. ; Prieto, Miguel L. ; Vande Voort, Jennifer L. ; Croarkin, Paul E. ; Hoberg, Astrid A. ; Kung, Simon ; Alarcon, Renato D. ; Keeth, Nicola ; Singh, Balwinder ; Bobo, William V. ; Frye, Mark A. | Frontiers Media | 2019-07-04T16:59:27ZBackground: Pharmacogenomic testing, specifically for pharmacokinetic (PK) and pharmacodynamic (PD) genetic variation, may contribute to a better understanding of baseline genetic differences in patients seeking treatment for depression, which [...]texto impreso
Gómez-Boronat, Miguel ; Isorna Alonso, Esther ; Armirotti, Andrea ; Delgado Saavedra, María Jesús ; Piomelli, Danielle ; Pedro Ormeño, Nuria de | Frontiers Media | 2019-05-07N-acylethanolamines (NAEs) are a family of endogenous lipid signaling molecules that are involved in regulation of energy homeostasis in vertebrates with a putative role on circadian system. The aim of this work was to study the existence of dai[...]texto impreso
Time perception is studied with subjective or semi-objective psychophysical methods. With subjective methods, observers provide quantitative estimates of duration and data depict the psychophysical function relating subjective duration to object[...]
