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Public Library Science |
Documentos disponibles de esta editorial (37)
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Nieves Moreno, María ; Martínez de la Casa, Jose Maria ; Cifuentes Canorea, Pilar ; Sastre Ibáñez, Marina ; Santos Bueso, Enrique ; Sáenz Francés, Federico ; Morales Fernández, Laura ; García Feijoo, Julián | Public Library Science | 2017-07-05Purpose: Develop the first normative database of the thickness of every inner retinal layer in the macular area in a healthy, Caucasian population between 18 to 87 years old, using Spectralis Optical Coherence Tomography (OCT). Methods: On this [...]![]()
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Beltrán-Beck, Beatriz ; De la Fuente, Jose ; Garrido, Joseba M ; Aranaz Martín, Alicia ; Sevilla, Iker ; Villar, Margarita ; Boadella, Mariana ; Galindo, Ruth C ; Pérez de la Lastra, José M ; Moreno Cid, Juan A ; Fernández de Mera, Isabel G ; Alberdi, Pilar ; Santos, Gracia ; Ballesteros, Cristina ; Lyashchenko, Konstantin P ; Minguijón, Esmeralda ; Romero Martínez, Beatriz ; Juan Ferré, Lucia de ; Domínguez Rodríguez, Lucas ; Juste, Ramón ; Gortazar, Christian | Public Library Science | 2014Tuberculosis (TB) remains a pandemic affecting billions of people worldwide, thus stressing the need for new vaccines. Defining the correlates of vaccine protection is essential to achieve this goal. In this study, we used the wild boar model fo[...]![]()
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Ortiz, Tomás ; Poch, Joaquín ; Santos, Juan M. ; Requena, Carmen ; Martínez, Ana M. ; Ortiz Terán, Laura ; Turrero, Agustín ; Barcia, Juan ; Nogales, Ramón ; Calvo, Agustín ; Martínez, José M. ; Córdoba, José L. ; Pascual Leone, Álvaro | Public Library Science | 2011Over three months of intensive training with a tactile stimulation device, 18 blind and 10 blindfolded seeing subjects improved in their ability to identify geometric figures by touch. Seven blind subjects spontaneously reported 'visual qualia',[...]![]()
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Vicente-Tejedor, Javier ; Marchena, Miguel ; Ramirez, Laura ; García Ayuso, Diego ; Gómez Vicente, Violeta ; Sánchez Ramos, Celia ; Villa Polo, Pedro de la ; Germain, Francisco | Public Library Science | 2018-03-15Light causes damage to the retina (phototoxicity) and decreases photoreceptor responses to light. The most harmful component of visible light is the blue wavelength (400–500 nm). Different filters have been tested, but so far all of them allow p[...]![]()
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Hoz Montañana, María Rosa de ; Gallego Collado, Beatriz Isabel ; Ramírez Sebastián, Ana Isabel ; Rojas López, María Blanca ; Salazar Corral, Juan José ; Valiente Soriano, Francisco Javier ; Avilés Trigueros, Marcelino ; Villegas Pérez, María Paz ; Vidal Sanz, Manuel ; Triviño Casado, Alberto ; Ramirez Sebastian, Jose Manuel | Public Library Science | 2013-12-18In the mouse model of unilateral laser-induced ocular hypertension (OHT) the microglia in both the treated and the normotensive untreated contralateral eye have morphological signs of activation and up-regulation of MHC-II expression in comparis[...]![]()
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Domingo Martínez, Laura ; Barroso-Barcenilla, Fernando ; Cambra-Moo, Oscar | Public Library Science | 2015-03Isotopic studies of multi-taxa terrestrial vertebrate assemblages allow determination of paleoclimatic and paleoecological aspects on account of the different information supplied by each taxon. The late Campanian-early Maastrichtian “Lo Hueco” [...]![]()
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Cruz Conty, Maria Luisa de la ; Perez, Andrés ; Bezos Garrido, Javier ; Pages, Enrique ; Casal, Carmen ; Carpintero, Jesus ; Romero Martínez, Beatriz ; Domínguez Rodríguez, Lucas ; Barker, Christopher M ; Diaz, Rosa ; Álvarez Sánchez, Julio | Public Library Science | 2014Progress in control of bovine tuberculosis (bTB) is often not uniform, usually due to the effect of one or more sometimes unknown epidemiological factors impairing the success of eradication programs. Use of spatial analysis can help to identify[...]![]()
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Salazar Corral, Juan José ; Gallego-Pinazo, Roberto ; Hoz Montañana, María Rosa de ; Pinazo-Durán, María Dolores ; Rojas López, María Blanca ; Ramírez Sebastián, Ana Isabel ; Serrano Espinosa, Manuel ; Ramirez Sebastian, Jose Manuel | Public Library Science | 2013-06-07Tumour-suppressor genes, such as the p53 gene, produce proteins that inhibit cell division under adverse conditions, as in the case of DNA damage, radiation, hypoxia, or oxidative stress (OS). The p53 gene can arrest proliferation and trigger de[...]![]()
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Acevedo, Pelayo ; Romero Martínez, Beatriz ; Vicente, Joaquín ; Caracappa, Santo ; Galluzzo, Paola ; Marineo, Sandra ; Vicari, Domenico ; Torina, Alessandra ; Casal, Carmen ; De la Fuente, Jose ; Gortazar, Christian | Public Library Science | 2013Because of their relative simplicity and the barriers to gene flow, islands are ideal systems to study the distribution of biodiversity. However, the knowledge that can be extracted from this peculiar ecosystem regarding epidemiology of economic[...]![]()
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Camicia, Federico ; Celentano, Ana M. ; Johns, Malcolm E. ; Chan, John D. ; Maldonado, Lucas ; Vaca, Hugo ; Siervi, Nicolás Di ; Kamenetzky, Laura ; Gamo Albero, Ana María ; Ortega Gutiérrez, Silvia ; Martín Fontecha, María del Mar ; Davio, Carlos ; Marchant, Jonathan S. ; Rosenzvit, Mara C. | Public Library Science | 2018-02-09Background: Cestodes are a diverse group of parasites, some of them being agents of neglected diseases. In cestodes, little is known about the functional properties of G protein coupled receptors (GPCRs) which have proved to be highly druggable [...]![]()
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Investigation of mechanisms of information handling in neural assemblies involved in computational and cognitive tasks is a challenging problem. Synergetic cooperation of neurons in time domain, through synchronization of firing of multiple spat[...]![]()
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Reboredo, Mercedes ; Chang, Haisul C. Y. ; Barbero, Roberto ; Rodríguez Ortigosa, Carlos M. ; Pérez Vizcaino, Francisco ; Morán, Asunción ; García, Mónica ; Banales, Jesus ; Carreño, Norberto ; Alegre, Félix ; Herrero, Ignacio ; Quiroga, Jorge ; Prieto, Jesús ; Sangro, Bruno | Public Library Science | 2013-01-16Objective: Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol. Here we analyzed the effects of zolmitriptan on portal pressure and its potential interaction with[...]