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Título:
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Uncontrolled SFK-mediated protein trafficking in prion and Alzheimer's disease
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Autores:
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Malaga-Trillo, Edward ;
Ochs, Katharina
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Tipo de documento:
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texto impreso
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Editorial:
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Taylor & Francis, 2019-02-06T14:45:37Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Prions and Amyloid beta (Abeta) peptides induce synaptic damage via complex mechanisms that include the pathological alteration of intracellular signaling cascades. The host-encoded cellular prion protein (PrP(C)) acts as a high-affinity cell surface receptor for both toxic species and it can modulate the endocytic trafficking of the N-methyl D-aspartate (NMDA) receptor and
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En línea:
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http://doi.org/10.1080/19336896.2016.1221873
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