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Título:
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Chronic exposure to biomass fuel smoke and markers of endothelial inflammation
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Autores:
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Caravedo, M. A. ;
Herrera, P. M. ;
Mongilardi, N. ;
de Ferrari, A. ;
Davila-Roman, V. G. ;
Gilman, R. H. ;
Wise, R. A. ;
Miele, C. H. ;
Miranda, J. J. ;
Checkley, W.
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Tipo de documento:
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texto impreso
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Editorial:
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Wiley, 2019-02-06T14:52:36Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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Indoor smoke exposure may affect cardiovascular disease (CVD) risk via lung-mediated inflammation, oxidative stress, and endothelial inflammation. We sought to explore the association between indoor smoke exposure from burning biomass fuels and a selected group of markers for endothelial inflammation. We compared serum concentrations of amyloid A protein, E-selectin, soluble intercellular adhesion molecule 1 (ICAM-1) and VCAM-1, von Willebrand factor (vWF), and high-sensitivity C-reactive protein (hs-CRP) in 228 biomass-exposed vs. 228 non-exposed participants living in Puno, Peru. Average age was 56 years (s.d. = 13), average BMI was 26.5 kg/m(2) (s.d. = 4.4), 48% were male, 59.4% completed high school, and 2% reported a physician diagnosis of CVD. In unadjusted analysis, serum levels of soluble ICAM-1 (330 vs. 302 ng/ml; P
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En línea:
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http://doi.org/10.1111/ina.12259
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