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Título:
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The seasonality of tuberculosis, sunlight, vitamin D, and household crowding
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Autores:
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Wingfield, Tom ;
Schumacher, Samuel G. ;
Sandhu, Gurjinder ;
Tovar, Marco A. ;
Zevallos, Karine ;
Baldwin, Matthew R. ;
Montoya, Rosario ;
Ramos, Eric S. ;
Jongkaewwattana, Chulanee ;
Lewis, James J. ;
Gilman, Robert H. ;
Friedland, Jon S. ;
Evans, Carlton A.
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Tipo de documento:
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texto impreso
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Editorial:
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Oxford University Press, 2020-06-10T18:12:15Z
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Nota general:
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info:eu-repo/semantics/restrictedAccess
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
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Idiomas:
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Inglés
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Palabras clave:
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Editados por otras instituciones
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Artículos
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Artículos en revistas indizadas
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Resumen:
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BACKGROUND: Unlike other respiratory infections, tuberculosis diagnoses increase in summer. We performed an ecological analysis of this paradoxical seasonality in a Peruvian shantytown over 4 years. METHODS: Tuberculosis symptom-onset and diagnosis dates were recorded for 852 patients. Their tuberculosis-exposed cohabitants were tested for tuberculosis infection with the tuberculin skin test (n = 1389) and QuantiFERON assay (n = 576) and vitamin D concentrations (n = 195) quantified from randomly selected cohabitants. Crowding was calculated for all tuberculosis-affected households and daily sunlight records obtained. RESULTS: Fifty-seven percent of vitamin D measurements revealed deficiency (
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En línea:
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http://doi.org/10.1093/infdis/jiu121
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