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106 búsqueda de la palabra clave 'Materia = Ciencias Biomédicas: Biología: Neurociencias'
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La conciencia ecológica se construye a base de creencias, ya tengan éstas una base científica o ficcional. La divulgación de los conocimientos científicos adolece de la seducción emocional que tienen las narrativas de ficción, que pueden llegar [...]![]()
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Martínez Herrero, Avelino | 2017-09La historia de la interlocución entre las ciencias de la naturaleza y las religiones (y sus teologías) ha alcanzado probablemente su tensión máxima en el debate acerca de los orígenes de la realidad en sus diversos ámbitos (físico-cosmológico, b[...]![]()
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Llorente Berzal, Álvaro ; Terzian, Ana Luisa B. ; Di Marzo, Vincenzo ; Micale, Vincenzo ; Viveros, María Paz ; Wotjak, Carsten T. | Springer | 2015-08Rationale The contribution of two major endocannabinoids, 2-arachidonoylglycerol (2-AG) and anandamide (AEA), in the regulation of fear expression is still unknown. Objectives We analyzed the role of different players of the endocannabinoid syst[...]![]()
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Cannabis sativa preparations are among the illicit drugs most commonly used by young people, including pregnant women. The endocannabinoid (eCB) system, which is involved in the regulation of emotional and motivational homeostasis, synaptic plas[...]![]()
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Dasilva, Miguel ; Navarro-Guzman, Alvaro ; Ortiz-Romero, Paula ; Camassa, Alessandra ; Muñoz-Cespedes, Alberto ; Campuzano, Victoria ; Sanchez-Vives, María V. | Springer | 2019-08-30Williams–Beuren syndrome (WBS) is a rare neurodevelopmental disorder characterized by moderate intellectual disability and learning difficulties alongside behavioral abnormalities such as hypersociability. Several structural and functional brain[...]![]()
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Martínez de Toda Cabeza, Irene ; Miguélez, Lara ; Vida, Carmen ; Carro, Eva ; Fuente del Rey, Mónica de la | IOS Press | 2019-09-03Oxidative stress plays an essential and early role in the pathophysiology of Alzheimer’s disease (AD). Alterations in the redox state in AD and in mild cognitive impairment (MCI) patients appear in the brain and at peripheral level. Given that i[...]![]()
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Morona Arribas, Ruth ; Bandín Carazo, Sandra ; López Redondo, Jesús María ; Moreno García, Nerea ; González Gallegos, Agustín | Wiley | 2020-03-11The early patterning of the thalamus during embryonic development defines rostral and caudal progenitor domains, which are conserved from fishes to mammals. However, the subsequent developmental mechanisms that lead to the adult thalamic configu[...]![]()
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In the present work we study how sensory inputs conveyed by nerve fibers in the form of spatiotemporal patterns generate different responses in the central nervous system (CNS) depending on the physical characteristics of the stimulus applied an[...]![]()
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Ruiz Calvo, Andrea ; Bajo-Grañeras, Raquel ; Maroto, Irene B. ; Zian, Debora ; Grabner, Gernot F. ; García-Taboada, Elena ; Resel, Eva ; Zechner, Rudolf ; Zimmermann, Robert ; Ortega-Gutiérrez, Silvia ; Galve Roperh, Ismael ; Bellocchio, Luigi ; Guzmán, Manuel | Elsevier | 2019-05-15Cannabinoids exert neuroprotection in a wide array of preclinical models. A number of these studies has focused on cannabinoid CB1 receptors in striatal medium spiny neurons (MSNs) and the most characteristic MSN-degenerative disease, Huntington[...]![]()
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Mela Rivas, Virginia ; Díaz, Francisca ; López Rodríguez, Ana Belén ; Vázquez, María Jesús ; Gertler, Arieh ; Argente, Jesús ; Tena-Sempere, Manuel ; Viveros, María Paz ; Chowen, Julie A. | Oxford University Press | 2015-07Leptin is important in the development of neuroendocrine circuits involved in metabolic control. As both leptin and metabolism influence pubertal development, we hypothesized that early changes in leptin signaling could also modulate hypothalami[...]![]()
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Blanco Imperiali, Ayelén M. ; Sánchez Bretaño, Aída ; Delgado Saavedra, María Jesús ; Valenciano González, Ana Isabel | Wiley Periodicals | 2016Ghrelin O-acyltransferase (GOAT) is the enzyme responsible for acylation of ghrelin, a gut-brain hormone with important roles in many physiological functions in vertebrates. Many aspects of GOAT remain to be elucidated, especially in fish, and p[...]![]()
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Cano Barquilla, María del Pilar | Universidad Complutense de Madrid, Servicio de Publicaciones | 2003Los ritmos biológicos, particularmente los ritmos circadianos, son esenciales en la organización temporal de los seres vivos. En mamíferos envejecidos, todas las características rítmicas cambian, aunque no todos al mismo tiempo ni de forma simul[...]![]()
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Gomes, Felipe V. ; Issy, Ana Carolina ; Ferreira, Frederico R. ; Viveros, María Paz ; Del Bel, Elaine A. ; Guimarães, Francisco S. | Oxford University Press | 2015-01-24Background: Preclinical and clinical data suggest that cannabidiol (CBD), a major non-psychotomimetic compound from Cannabis sativa, induces antipsychotic-like effects. However, the antipsychotic properties of repeated CBD treatment have been po[...]![]()
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Bravo Ferrer, Isbel ; Cuartero Desviat, María Isabel ; Zarruk, Juan G. ; Pradillo, Jesús M. ; Hurtado Moreno, Olivia ; Romera, Victor G. ; Díaz Alonso, Javier ; García Segura, Juan Manuel ; Guzmán, Manuel ; Lizasoaín, Ignacio ; Galve Roperh, Ismael ; Moro, María A. | American Heart Association | 2017-01Background and Purpose—Stroke is a leading cause of adult disability characterized by physical, cognitive, and emotional disturbances. Unfortunately, pharmacological options are scarce. The cannabinoid type-2 receptor (CB2R) is neuroprotective i[...]![]()
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Gragera Martínez, Raquel de los Reyes | Universidad Complutense de Madrid, Servicio de Publicaciones | 1993Los capilares cerebelosos constituyen la principal estructura constituyente de la barrera hematoencefalica en esta región cerebral, junto con el envoltorio glial perivascular. Las técnicas de microscopia electrónica convencional nos han permitid[...]